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癌症幸存者的运动:研究综述

Exercise in cancer survivors: an overview of research.

作者信息

Courneya Kerry S

机构信息

University of Alberta, Edmonton, Alberta, Canada.

出版信息

Med Sci Sports Exerc. 2003 Nov;35(11):1846-52. doi: 10.1249/01.MSS.0000093622.41587.B6.

DOI:10.1249/01.MSS.0000093622.41587.B6
PMID:14600549
Abstract

PURPOSE

To provide an overview of research that has examined exercise in cancer survivors including recently completed trials at the University of Alberta.

METHODS

A search of published studies using electronic data bases and previous review articles. The review is divided into breast and nonbreast cancers, during and after treatment, and trials from the University of Alberta.

RESULTS

Forty-seven published studies were located and summarized plus four trials from the University of Alberta. Almost all studies showed beneficial effects of exercise in breast and nonbreast cancer groups alike as well as during and after cancer treatment.

CONCLUSION

Preliminary research suggests that exercise may be an effective intervention for enhancing quality of life (QOL) in cancer survivors. The effects of exercise on biomarkers, cancer recurrence, other diseases, and overall survival are unknown. Future research is needed to extend our knowledge beyond breast cancer survivors, conduct second generation studies in breast cancer survivors, examine mechanisms for changes in QOL, compare exercise with other QOL interventions, and examine biomarkers, cancer recurrence, and survival.

摘要

目的

概述关于癌症幸存者运动情况的研究,包括阿尔伯塔大学最近完成的试验。

方法

通过电子数据库和以往的综述文章检索已发表的研究。该综述分为乳腺癌和非乳腺癌、治疗期间和治疗后,以及阿尔伯塔大学的试验。

结果

找到了47项已发表的研究并进行了总结,外加阿尔伯塔大学的4项试验。几乎所有研究都表明,运动对乳腺癌和非乳腺癌群体以及癌症治疗期间和治疗后都有有益影响。

结论

初步研究表明,运动可能是提高癌症幸存者生活质量(QOL)的有效干预措施。运动对生物标志物、癌症复发、其他疾病和总生存期的影响尚不清楚。未来需要开展研究,以拓展我们对乳腺癌幸存者以外人群的认识,在乳腺癌幸存者中进行第二代研究,研究生活质量改善的机制,将运动与其他生活质量干预措施进行比较,并研究生物标志物、癌症复发和生存期。

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