Evans Meirion R, Ribeiro C Donald, Salmon Roland L
Dept. of Epidemiology, Statistics and Public Health, University of Wales College of Medicine, Cardiff CF14 4XN, Wales, United Kingdom.
Emerg Infect Dis. 2003 Oct;9(10):1219-25. doi: 10.3201/eid0910.020823.
Campylobacter is the most common cause of bacterial gastroenteritis worldwide, yet the etiology of this infection remains only partly explained. In a retrospective cohort study, we compared 213 sporadic campylobacter case-patients with 1,144 patients with negative fecal samples. Information was obtained on food history, animal contact, foreign travel, leisure activities, medical conditions, and medication use. Eating chicken, eating food from a fried chicken outlet, eating salad vegetables, drinking bottled water, and direct contact with cows or calves were all independently associated with infection. The population-attributable fractions for these risk factors explained nearly 70% of sporadic campylobacter infections. Eating chicken is a well-established risk factor, but consuming salad and bottled water are not. The association with salad may be explained by cross-contamination of food within the home, but the possibility that natural mineral water is a risk factor for campylobacter infection could have wide public health implications.
弯曲杆菌是全球细菌性肠胃炎最常见的病因，但这种感染的病因仍只得到部分解释。在一项回顾性队列研究中，我们将213例散发性弯曲杆菌病例患者与1144例粪便样本呈阴性的患者进行了比较。获取了关于饮食史、动物接触史、出国旅行、休闲活动、健康状况和用药情况的信息。食用鸡肉、食用炸鸡店的食物、食用沙拉蔬菜、饮用瓶装水以及直接接触奶牛或小牛均与感染独立相关。这些危险因素的人群归因分数解释了近70%的散发性弯曲杆菌感染病例。食用鸡肉是一个已确定的危险因素，但食用沙拉和饮用瓶装水并非如此。与沙拉的关联可能是由于家庭内部食物的交叉污染，但天然矿泉水是弯曲杆菌感染危险因素的可能性可能对公共卫生有广泛影响。
