Clark Daniel O, Tu Wanzhu, Weiner Michael, Murray Michael D
Indiana University Center for Aging Research, Indianapolis, 46202, USA.
Heart Lung. 2003 Nov-Dec;32(6):391-401. doi: 10.1016/j.hrtlng.2003.07.005.
Improving health-related quality of life (HRQL) is a primary goal in the treatment of patients with congestive heart failure (CHF), yet few studies have explored correlates of HRQL among CHF patients.
We report on the association of demographic and pathophysiologic measures, social-cognitive measures, and environmental variables with HRQL as measured by the Kansas City Cardiomyopathy Questionnaire (KCCQ), Chronic Heart Failure (CHQ), and a single question of perceived overall health (PH).
Cross-sectional data were obtained from the baseline interview and electronic medical records of 212 patients 50 years of age and older who were enrolled during the first 7 months of a medication adherence study.
Mean age was 63; 32% were male; 53% were black; the mean Charlson comorbidity score was 3.7; and the mean New York Heart Association class was 2.1. Correlations between KCCQ and CHQ subscale scores and PH ranged from 0.16 to 0.37. Multivariate regression analyses showed that the pathophysiologic measures ejection fraction and comorbidity were not associated with any of the HRQL measures. Overall PH was associated with greater age and more positive health beliefs. Persons of greater age, males, and black respondents had higher CHF-specific HRQL scores, as did persons reporting more positive health beliefs, greater income, social support, and communication with their physician. Variance explained ranged from 14 to 33%.
These cross-sectional data highlight the potential significance of social and behavioral factors in CHF-specific HRQL.
改善健康相关生活质量(HRQL)是充血性心力衰竭(CHF)患者治疗的主要目标,但很少有研究探讨CHF患者中HRQL的相关因素。
我们报告了人口统计学和病理生理学指标、社会认知指标以及环境变量与通过堪萨斯城心肌病问卷(KCCQ)、慢性心力衰竭问卷(CHQ)和一个关于总体健康感知的单一问题(PH)所测量的HRQL之间的关联。
横断面数据来自于一项药物依从性研究前7个月入组的212名50岁及以上患者的基线访谈和电子病历。
平均年龄为63岁;32%为男性;53%为黑人;Charlson合并症评分平均为3.7;纽约心脏协会心功能分级平均为2.1。KCCQ和CHQ分量表得分与PH之间的相关性范围为0.16至0.37。多变量回归分析表明,病理生理学指标射血分数和合并症与任何HRQL指标均无关联。总体PH与年龄较大和更积极的健康信念相关。年龄较大者、男性和黑人受访者的CHF特异性HRQL得分较高,报告更积极健康信念、收入更高、社会支持更多以及与医生沟通更多的人得分也较高。解释的方差范围为14%至33%。
这些横断面数据突出了社会和行为因素在CHF特异性HRQL中的潜在重要性。