Schmitt F C
Department of Pathology, Botucatu School of Medicine, UNESP, Botucatu, São Paulo, Brazil.
Diagn Cytopathol. 1992;8(6):596-9. doi: 10.1002/dc.2840080612.
Cytomorphologic characteristics of smears from fine-needle aspirates (FNA) of three cases of sinus histiocytosis with massive lymphadenopathy (SHML) (Rosai-Dorfman disease) are described. All aspirates showed mature lymphocytes, plasma cells, and large pale histiocytes with well-preserved lymphocytes within the cytoplasm (lymphocytophagocytosis). The cases were confirmed by surgical biopsy, and the immunohistochemical findings suggested a macrophage origin for this lesion. The value of FNA analysis as an aid to diagnosis of SHML is discussed.
描述了3例伴有巨大淋巴结病的窦性组织细胞增生症（SHML）（罗萨伊-多夫曼病）细针穿刺抽吸物（FNA）涂片的细胞形态学特征。所有抽吸物均显示成熟淋巴细胞、浆细胞和胞质内有保存完好淋巴细胞的大的淡染组织细胞（淋巴细胞吞噬现象）。这些病例经手术活检确诊，免疫组化结果提示该病变起源于巨噬细胞。讨论了FNA分析对SHML诊断的辅助价值。
