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APHE-1 and APHE-2, two new antimicrobial and cytotoxic antibiotics. I. Taxonomy, fermentation, isolation and biological activity.

作者信息

Fidalgo M L, Alonso J L, Soliveri J, Arias M E

机构信息

Departamento de Microbiología y Parasitología, Universidad de Alcalá de Henares, Madrid, Spain.

出版信息

J Antibiot (Tokyo). 1992 Nov;45(11):1753-8. doi: 10.7164/antibiotics.45.1753.

DOI:10.7164/antibiotics.45.1753
PMID:1468982
Abstract

APHE-1 and APHE-2 are two new antibiotics produced by Streptoverticillium griseocarneum NCIMB 40447. They exhibited a remarkable cytotoxic activity against several tumor cell lines from different origin. Furthermore, they showed weak antimicrobial activity against Gram-positive bacteria, filamentous fungi and yeasts.

摘要

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