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一例经血清学诊断由犬钩口线虫引起的皮肤幼虫移行症的人类病例。

A serologically diagnosed human case of cutaneous larva migrans caused by Ancylostoma caninum.

作者信息

Kwon In-Ho, Kim Hyung-Su, Lee Jong-Hee, Choi Min-Ho, Chai Jong-Yil, Nakamura-Uchiyama Fukumi, Nawa Yukifumi, Cho Kwang-Hyun

机构信息

Department of Dermatology, Seoul National University College of Medicine, Seoul 110-744, Republic of Korea.

出版信息

Korean J Parasitol. 2003 Dec;41(4):233-7. doi: 10.3347/kjp.2003.41.4.233.

Abstract

A 15-year-old boy, who had recently arrived back from a trip to Cambodia for a missionary camp, presented with several serpiginous thread-like skin lesions that began as small papules on the left upper extremities 2 weeks before his visit to Hospital. The skin lesions were pruritic and erythematous, and had migrated to the chest and abdomen. The histopathological findings showed only lymphocytic and eosinophilic infiltrations in the dermis of the biopsied skin lesion. The patient's serum reacted strongly to the Ancylostoma caninum antigen by an ELISA method. Therefore, he was diagnosed with cutaneous larva migrans by A. caninum. After the oral administration of albendazole and ivermectin, the skin lesions resolved without recurrence. This is the first reported case of a cutaneous larva migrans caused by Ancylostoma canimum diagnosed serologically using ELISA in Korea.

摘要

一名15岁男孩最近刚从柬埔寨的一个传教士营地旅行归来,在前往医院就诊前2周,他的左上肢出现了几处蜿蜒的线状皮肤病变,最初为小丘疹。这些皮肤病变瘙痒且呈红斑状,已蔓延至胸部和腹部。组织病理学检查结果显示,活检皮肤病变的真皮层仅有淋巴细胞和嗜酸性粒细胞浸润。通过酶联免疫吸附测定法(ELISA),患者血清对犬钩口线虫抗原反应强烈。因此,他被诊断为犬钩口线虫引起的皮肤幼虫移行症。口服阿苯达唑和伊维菌素后,皮肤病变消退且未复发。这是韩国首例通过ELISA血清学诊断为犬钩口线虫引起的皮肤幼虫移行症的报告病例。

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本文引用的文献

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THIABENDAZOLE EFFECTIVENESS IN CREEPING ERUPTION.
Arch Dermatol. 1965 May;91:427-9. doi: 10.1001/archderm.1965.01600110013004.
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Cutaneous larva migrans.皮肤幼虫移行症
South Med J. 1993 Nov;86(11):1311-3. doi: 10.1097/00007611-199311000-00032.

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