Zibetti A, Cazzullo C L, Smeraldi E, Scorza-Smeraldi R
Boll Ist Sieroter Milan. 1978 Jan 31;56(6):539-43.
Considerable evidence suggests the existence of significant differences of HLA distribution between M.S. patients and normal healthy subjects of the same population. In the present work we investigate whether the antigen DW2 may be a better marker for M.S. than the specificities at the loci A and B by means of in vitro one-way mixed lymphocyte cultures.
大量证据表明，在同一人群中，多发性硬化症患者与正常健康受试者之间的HLA分布存在显著差异。在本研究中，我们通过体外单向混合淋巴细胞培养，研究抗原DW2是否可能是比A和B位点特异性更好的多发性硬化症标志物。
