van den Broek Nynke
Reproductive Health, Liverpool School of Tropical Medicine, Liverpool, UK.
Br Med Bull. 2003;67:149-60. doi: 10.1093/bmb/ldg004.
Anaemia in pregnancy is a common and worldwide problem that deserves more attention. For many developing countries, prevalence rates of up to 75% are reported. Anaemia is frequently severe in these situations and can be expected to contribute significantly to maternal mortality and morbidity. After a discussion of definitions, screening for anaemia and prevalence, the relationship between anaemia and maternal mortality and morbidity will be reviewed. Micronutrient deficiency and especially iron deficiency is believed to be the main underlying cause for anaemia. More recently the role of vitamin A deficiency as a contributing factor to anaemia has also been examined. The difficulties of assessment of micronutrient sufficiency or deficiency in pregnancy are described, as is the interaction between infection and micronutrient deficiency states.
孕期贫血是一个普遍存在且值得更多关注的全球性问题。许多发展中国家报告的患病率高达75%。在这些情况下,贫血往往很严重,预计会对孕产妇死亡率和发病率产生重大影响。在讨论了贫血的定义、筛查及患病率之后,将对贫血与孕产妇死亡率和发病率之间的关系进行综述。微量营养素缺乏,尤其是缺铁,被认为是贫血的主要潜在原因。最近,维生素A缺乏作为贫血的一个促成因素的作用也得到了研究。文中描述了评估孕期微量营养素充足或缺乏的困难,以及感染与微量营养素缺乏状态之间的相互作用。