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儿童哮喘患者静息能量消耗增加:这会导致生长发育迟缓吗?

Increased resting energy expenditure in childhood asthma: does this contribute towards growth failure?

作者信息

Zeitlin S R, Bond S, Wootton S, Gregson R K, Radford M

机构信息

Department of Child Health, Southampton General Hospital.

出版信息

Arch Dis Child. 1992 Nov;67(11):1366-9. doi: 10.1136/adc.67.11.1366.

DOI:10.1136/adc.67.11.1366
PMID:1471888
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1793770/
Abstract

In order to determine whether or not there was a relationship between disorders of growth in children suffering from asthma and either increased resting energy expenditure or inadequate energy intake, a group of 34 children suffering from perennial symptoms were studied. A control group matched with the asthmatic children for sex and fat free mass were similarly studied. The children kept seven day records of weighed food intake. Basal metabolic rate was measured on one occasion in the fasted state by means of indirect calorimetry using the ventilated hood technique. The asthmatic children kept a 28 day record of peak expiratory flow rates, asthma symptoms, and medication usage. The asthmatic children expended significantly more energy at rest than their matched controls in absolute terms (14%). There was no correlation between height or height SD score and any parameter of energy balance. The causes of these finding are as yet speculative.

摘要

为了确定患有哮喘的儿童生长障碍与静息能量消耗增加或能量摄入不足之间是否存在关联,对一组34名患有常年症状的儿童进行了研究。同时对一组在性别和去脂体重方面与哮喘儿童相匹配的对照组儿童进行了类似研究。这些儿童记录了七天的食物摄入量。通过使用通风罩技术的间接量热法在禁食状态下测量了一次基础代谢率。哮喘儿童记录了28天的呼气峰值流速、哮喘症状和药物使用情况。从绝对值来看,哮喘儿童在静息状态下消耗的能量比与之匹配的对照组儿童显著更多(14%)。身高或身高标准差评分与能量平衡的任何参数之间均无相关性。这些发现的原因目前仍属推测。

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