孕期抗病毒及抗逆转录病毒药物的使用。
Antiviral and antiretroviral use in pregnancy.
作者信息
Money Deborah M
机构信息
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Room 2H30, University of British Columbia, 4500 Oak Street, Vancouver, BC, V6H 3N1, Canada.
出版信息
Obstet Gynecol Clin North Am. 2003 Dec;30(4):731-49, vii. doi: 10.1016/s0889-8545(03)00089-5.
The history of antiviral and antiretroviral therapy is recent compared with many other medical therapies, including traditional antibiotics in pregnancy. There are few long-term data on which to base decisions of management in pregnancy. Accessing up-to-date information is critical to optimizing the safety of care for mothers and their infants. Exposure to medications in pregnancy can be toxic to a fetus in a gestational age-dependent manner. Determination of safe medications for pregnancy must take into consideration the need for certain medications and the possibility of inadvertent exposure in early pregnancy because of unplanned pregnancies. This article reviews the most commonly used antiviral and antiretroviral agents and places emphasis on the issues regarding use in pregnancy.
与许多其他医学疗法（包括孕期使用的传统抗生素）相比，抗病毒和抗逆转录病毒疗法的历史较短。几乎没有长期数据可作为孕期管理决策的依据。获取最新信息对于优化母婴护理安全至关重要。孕期接触药物可能会以与孕周相关的方式对胎儿产生毒性。确定孕期安全用药必须考虑到某些药物的必要性以及由于意外怀孕而在孕早期意外接触药物的可能性。本文回顾了最常用的抗病毒和抗逆转录病毒药物，并重点关注孕期用药相关问题。
Zotero 插件