Miller Frank R, Watson Daniel, Boseley Mark
Department of Otolaryngology-HNS, University of Texas Health Science Center-San Antonio, 78229-3900, USA.
Otolaryngol Head Neck Surg. 2004 Jan;130(1):73-9. doi: 10.1016/j.otohns.2003.09.015.
The successful surgical management of obstructive sleep apnea (OSA) requires surgical procedures that address both retropalatal and retrolingual airway obstruction. The Genial Bone Advancement Trephine (GBAT) system is a new, 1-step system that allows for isolation and advancement of the genioglossus muscle via a guided trephine system. The purpose of this project was to describe our experience using the GBAT system to perform genioglossus advancement (GGA) in conjunction with uvulopalatopharyngoplasty (UPPP) in the surgical management of OSA.
Retrospective analysis of 35 consecutive patients undergoing GGA using the GBAT system in conjunction with UPPP for the management of OSA during a 3-year period (1999 to 2002).
Twenty-four patients had complete preoperative and postoperative polysomnographic data. A 70% reduction in the Respiratory Disturbance Index (RDI) and Apnea Index (AI) in the preoperative versus postoperative PSG (RDI, 52.9 +/- 17.1 versus 15.9 +/- 7.5; AI, 20.1 +/- 6.7 versus 6.1 +/- 4.5; P < or = 0.0001). The lowest oxygen desaturation increased from 80% to 88% (P = 0.0002), and the posterior airway increased from 7.9 to 12.6 mm (P < 0.0001). With a surgical cure defined as a greater than 50% reduction in the RDI and a final postoperative RDI of less than 20 events per hour, the true surgical cure rate was 67% (16 of 24 patients).
The GBAT system performed in conjunction with UPPP can produce significant reductions in RDI and AI while improving the oxygen desaturation and enlarging the posterior airway space. The effective cure rates using the GBAT system are in agreement with previous reports in the literature using various GGA techniques. The GBAT may have some advantages in terms of simplicity and safety.
阻塞性睡眠呼吸暂停(OSA)的成功手术治疗需要针对腭后和舌后气道阻塞的手术方法。颏骨前移环钻(GBAT)系统是一种新型的一步式系统,可通过引导环钻系统分离并前移颏舌肌。本项目的目的是描述我们使用GBAT系统在OSA手术治疗中联合悬雍垂腭咽成形术(UPPP)进行颏舌肌前移(GGA)的经验。
对1999年至2002年3年间连续35例使用GBAT系统联合UPPP进行GGA治疗OSA的患者进行回顾性分析。
24例患者有完整的术前和术后多导睡眠图数据。术前与术后多导睡眠图中呼吸紊乱指数(RDI)和呼吸暂停指数(AI)降低了70%(RDI,52.9±17.1对15.9±7.5;AI,20.1±6.7对6.1±4.5;P≤0.0001)。最低氧饱和度从80%提高到88%(P = 0.0002),后气道从7.9毫米增加到12.6毫米(P < 0.0001)。将手术治愈定义为RDI降低大于50%且术后最终RDI每小时少于20次事件,实际手术治愈率为67%(24例患者中的16例)。
GBAT系统联合UPPP可显著降低RDI和AI,同时改善氧饱和度并扩大后气道空间。使用GBAT系统的有效治愈率与文献中先前使用各种GGA技术的报道一致。GBAT在简单性和安全性方面可能具有一些优势。