Youssef Diaa T A
Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
J Nat Prod. 2004 Jan;67(1):112-4. doi: 10.1021/np0340192.
Tasnemoxides A-C (1-3), three new cytotoxic cyclic norsestertepene peroxides, were isolated from the Red Sea sponge Diacarnus erythraenus, together with the known compound sigmosceptrellin B (4). The structural determination of the isolated compounds was based on extensive 1D and 2D NMR studies and mass spectral determinations. Compounds 1-3 showed moderate cytotoxicity against three cancer cell lines.
从红海海绵红皮迪亚卡恩海绵中分离出三种新的具有细胞毒性的环状降倍半萜过氧化物塔斯奈莫氧化物A - C（1 - 3），以及已知化合物西格莫西普特雷林B（4）。所分离化合物的结构测定基于广泛的一维和二维核磁共振研究以及质谱测定。化合物1 - 3对三种癌细胞系显示出中等细胞毒性。
