Ferch Richard D, Shad Amjad, Cadoux-Hudson Tom A D, Teddy Peter J
Department of Neurosurgery, John Hunter Hospital and University of Newcastle, Newcastle, Australia.
J Neurosurg. 2004 Jan;100(1 Suppl Spine):13-9. doi: 10.3171/spi.2004.100.1.0013.
Cervical myelopathy may develop as a result of spinal cord compression with or without deformity. The effect of persistent kyphotic deformity on the ability of the cervical cord to recover following decompressive surgery is not known.
Between 1997 and 2000, a total of 28 patients with progressive myelopathy and kyphotic deformity underwent anterior decompression, deformity correction (0-4 degrees of lordosis), and fusion with anterior plating. Patients received clinical and radiological follow-up care, with independent analysis. Variables assessed included patient characteristics, severity of preoperative myelopathy, neck pain, and cervical sagittal alignment. Twenty-six patients (93%) underwent follow-up review for a minimum of 18 months. Two patients died: one died in the perioperative period and was excluded from further analysis, and in the other only 3 months of follow-up data could be obtained. Local deformity was corrected to neutral or lordosis in 24 cases (89%), and the overall cervical curve was corrected to neutral or lordosis in 20 cases (74%). There was a significant improvement in myelopathy scores in those patients in whom the target (0 to 4 degrees of lordosis) local angle was achieved (p = 0.04). There was a variable change in overall cervical sagittal alignment following local correction. Improvement in myelopathy was unrelated to patient age, previous surgery, or number of segments fused. Improvement in pain score was not related to correction of kyphotic angle.
The correction of sagittal alignment may promote recovery in spinal cord function in patients with kyphotic deformity.
颈椎脊髓病可能因脊髓受压伴或不伴畸形而发生。持续的后凸畸形对减压手术后颈髓恢复能力的影响尚不清楚。
在1997年至2000年期间,共有28例进行性脊髓病和后凸畸形患者接受了前路减压、畸形矫正(前凸0至4度)以及前路钢板融合术。患者接受临床和影像学随访,并进行独立分析。评估的变量包括患者特征、术前脊髓病严重程度、颈部疼痛和颈椎矢状位对线情况。26例患者(93%)接受了至少18个月的随访复查。2例患者死亡:1例在围手术期死亡,被排除在进一步分析之外,另1例仅获得了3个月的随访数据。24例(89%)患者的局部畸形被矫正至中立位或前凸位,20例(74%)患者的整体颈椎曲度被矫正至中立位或前凸位。在达到目标(前凸0至4度)局部角度的患者中,脊髓病评分有显著改善(p = 0.04)。局部矫正后,整体颈椎矢状位对线有不同程度的变化。脊髓病的改善与患者年龄、既往手术或融合节段数量无关。疼痛评分的改善与后凸角的矫正无关。
矢状位对线的矫正可能促进后凸畸形患者脊髓功能的恢复。