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医院获得性军团菌病——一例病例报告及文献综述

Nosocomial Legionnaire's disease--a case report and review of the literature.

作者信息

Woo J H, Kim S A, Park C S, Choi T Y, Chang I C, Lee I S

机构信息

Department of Internal Medicine, Soon Chun Hyang University, College of Medicine, Seoul, Korea.

出版信息

Korean J Intern Med. 1992 Jan;7(1):68-72. doi: 10.3904/kjim.1992.7.1.68.

DOI:10.3904/kjim.1992.7.1.68
PMID:1477034
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4532100/
Abstract

We report a case of nosocomial legionellosis in a 63 year-old man who was managed with neurosurgery under the diagnosis of subarachnoidal hemorrhage and complicated pneumonia in the intensive care unit. A legionella species was reported from sputum culture and direct immunofluorescent antibody test revealed L. pneumophila (serogroup 2). Our patient's pneumonia was cured with medical therapy including erythromycin and was the first case of microbiologically confirmed legionellosis in Korea.

摘要

我们报告一例医院获得性军团菌病,患者为一名63岁男性,因蛛网膜下腔出血接受神经外科手术治疗,并在重症监护病房并发肺炎。痰培养报告分离出一种军团菌,直接免疫荧光抗体检测显示为嗜肺军团菌(血清型2)。我们的患者经包括红霉素在内的药物治疗后肺炎治愈,这是韩国首例经微生物学确诊的军团菌病病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba5a/4532100/a76d67e01552/kjim-7-1-68-12f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba5a/4532100/7af9d6703fc0/kjim-7-1-68-12f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba5a/4532100/9959afde117d/kjim-7-1-68-12f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba5a/4532100/a76d67e01552/kjim-7-1-68-12f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba5a/4532100/7af9d6703fc0/kjim-7-1-68-12f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba5a/4532100/9959afde117d/kjim-7-1-68-12f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba5a/4532100/a76d67e01552/kjim-7-1-68-12f3.jpg

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本文引用的文献

1
Susceptibility of Legionella pneumophila to twenty antimicrobial agents.嗜肺军团菌对二十种抗菌药物的敏感性
Antimicrob Agents Chemother. 1980 Sep;18(3):403-8. doi: 10.1128/AAC.18.3.403.
2
Legionnaires' disease: report of sixty-five nosocomially acquired cases of review of the literature.军团病:65例医院获得性病例报告及文献综述
Medicine (Baltimore). 1980 May;59(3):188-205.
3
Lack of evidence for person-to-person transmission of Legionnaires' disease.缺乏军团病人际传播的证据。
J Infect Dis. 1983 Feb;147(2):362. doi: 10.1093/infdis/147.2.362.
4
Susceptibility of Legionella pneumophila to chlorine in tap water.嗜肺军团菌对自来水中氯的敏感性。
Appl Environ Microbiol. 1983 Nov;46(5):1134-9. doi: 10.1128/aem.46.5.1134-1139.1983.
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Legionnaires' disease in a transplant unit: isolation of the causative agent from shower baths.移植病房中的军团病:从淋浴喷头中分离出病原体
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Ecology of Legionella pneumophila within water distribution systems.军团菌在水分配系统中的生态学。
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Mode of transmission of Legionella pneumophila. A critical review.嗜肺军团菌的传播方式。批判性综述。
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Potential in-hospital modes of transmission of Legionella pneumophila. Demonstration experiments for dissemination by showers, humidifiers, and rinsing of ventilation bag apparatus.嗜肺军团菌在医院内可能的传播方式。通过淋浴喷头、加湿器及通风袋装置冲洗进行传播的验证实验。
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A live avirulent mutant Legionella pneumophila vaccine induces protective immunity against lethal aerosol challenge.一种活的无毒力突变型嗜肺军团菌疫苗可诱导针对致死性气溶胶攻击的保护性免疫。
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Nosocomial Legionnaires' disease and use of medication nebulizers.
J Infect Dis. 1991 Mar;163(3):667-71. doi: 10.1093/infdis/163.3.667.