Beer W E, Smith A E, Kassab J Y, Smith P H, Rowland Payne C M
Gwynedd Hospital, Bangor, UK.
Dermatology. 1992;184(4):265-70. doi: 10.1159/000247564.
There is a widespread belief that psoriasis (Ps) and atopic dermatitis (AD) are clinically mutually exclusive. A prospective study was undertaken to record the concurrent and/or consecutive coincidence of the two conditions and any shared clinical features. Patients attending a dermatology clinic were systematically examined for the presence of Ps and/or AD. Nine hundred and eighty-three patients were studied--428 with Ps, 224 with AD, 45 with both Ps and AD, and 286 controls. Of AD patients 16.7% had Ps, and 9.5% of Ps patients had AD. In consecutive occurrences, Ps generally followed AD. The ratio of concurrent to consecutive incidences was 3:1. The two diseases are shown not to be mutually exclusive and may coexist in the same individual.
人们普遍认为银屑病(Ps)和特应性皮炎(AD)在临床上相互排斥。一项前瞻性研究旨在记录这两种疾病同时出现和/或相继出现的情况以及任何共同的临床特征。对皮肤科门诊的患者进行了系统性检查,以确定是否存在银屑病和/或特应性皮炎。共研究了983名患者,其中428名患有银屑病,224名患有特应性皮炎,45名同时患有银屑病和特应性皮炎,286名作为对照。在特应性皮炎患者中,16.7%患有银屑病,而在银屑病患者中,9.5%患有特应性皮炎。在相继出现的病例中,银屑病通常继发于特应性皮炎之后。同时出现与相继出现的发病率之比为3:1。研究表明,这两种疾病并非相互排斥,可能在同一个体中共存。