一种用于评估帕金森病运动障碍和残疾程度的简短量表：SPES/SCOPA量表
A short scale for the assessment of motor impairments and disabilities in Parkinson's disease: the SPES/SCOPA.
作者信息
Marinus J, Visser M, Stiggelbout A M, Rabey J Martin, Martínez-Martín P, Bonuccelli U, Kraus P H, van Hilten J J
机构信息
Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
出版信息
J Neurol Neurosurg Psychiatry. 2004 Mar;75(3):388-95. doi: 10.1136/jnnp.2003.017509.
OBJECTIVES
To evaluate the reliability and validity of the Short Parkinson's Evaluation Scale (SPES)/SCales for Outcomes in Parkinson's disease (SCOPA)-a short scale developed to assess motor function in patients with Parkinson's disease (PD).
METHODS
Eighty five patients with PD were assessed with the SPES/SCOPA, Unified Parkinson's Disease Rating Scale (UPDRS), Hoehn and Yahr (H&Y) scale, and Schwab and England (S&E) scale. Thirty four patients were examined twice by two different assessors who were blinded to each other's scores and test executions. Additionally, six items of the motor section of the SPES/SCOPA were assessed in nine patients and recorded on videotape to evaluate inter-rater and intra-rater reliability.
RESULTS
The reproducibility of the sum scores in the clinical assessments was high for all subscales of the SPES/SCOPA. Inter-rater reliability coefficients for individual items ranged from 0.27-0.83 in the motor impairment section, from 0.58-0.82 in the activities of daily living section, and from 0.65-0.92 in the motor complications section. Inter-rater reliability of the motor items in the video assessments ranged from 0.70-0.87 and intra-rater reliability ranged from 0.81-0.95. The correlation between related subscales of the SPES/SCOPA and UPDRS were all higher than 0.85, and both scales revealed similar correlations with other measures of disease severity. The mean time to complete the scales differed significantly (p<0.001) and measured 8.1 (SD 1.9) minutes for the SPES/SCOPA and 15.6 (SD 3.6) minutes for the UPDRS.
CONCLUSION
The SPES/SCOPA is a short, reliable, and valid scale that can adequately be used in both research and clinical practice.
目的
评估帕金森病简易评估量表（SPES）/帕金森病结局量表（SCOPA）——一种为评估帕金森病（PD）患者运动功能而开发的简短量表——的信度和效度。
方法
85例PD患者接受了SPES/SCOPA、统一帕金森病评定量表（UPDRS）、霍恩和亚尔（H&Y）量表以及施瓦布和英格兰（S&E）量表的评估。34例患者由两名互不了解对方评分和测试执行情况的不同评估者进行了两次检查。此外，对9例患者的SPES/SCOPA运动部分的6个项目进行了评估，并录制在录像带上，以评估评估者间和评估者内信度。
结果
SPES/SCOPA所有子量表临床评估总分的可重复性都很高。运动损害部分各项目的评估者间信度系数在0.27至0.83之间，日常生活活动部分在0.58至0.82之间，运动并发症部分在0.65至0.92之间。录像评估中运动项目的评估者间信度在0.70至0.87之间，评估者内信度在0.81至0.95之间。SPES/SCOPA相关子量表与UPDRS之间的相关性均高于0.85，且两个量表与其他疾病严重程度指标的相关性相似。完成量表的平均时间有显著差异（p<0.001），SPES/SCOPA为8.1（标准差1.9）分钟，UPDRS为15.6（标准差3.6）分钟。
结论
SPES/SCOPA是一种简短、可靠且有效的量表，可充分用于研究和临床实践。
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