Jabbur Nada S, Tuli Suhas, Barequet Irina S, O'Brien Terrence P
Refractive Surgery Service, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21093, USA.
J Cataract Refract Surg. 2004 Jan;30(1):110-4. doi: 10.1016/S0886-3350(03)00519-4.
To analyze the outcome of laser in situ keratomileusis (LASIK) in patients with pigment dispersion syndrome (PDS).
Outpatient ambulatory laser vision correction centers.
This noncomparative case series reviewed the medical records of 12 patients (22 eyes) who had clinical features consistent with PDS at the time of the initial preoperative refractive evaluation and had LASIK surgery.
Twenty eyes (90.9%) of 11 patients had an uneventful course after LASIK and a good final uncorrected visual acuity (mean follow-up 26 months). One patient (2 eyes) with PDS and suspicion of glaucoma on topical beta-blocker therapy had delayed healing, fluctuations in vision, and a lengthy visual recovery.
Corneal findings of PDS do not appear to affect the intraoperative or postoperative outcomes of LASIK. However, patients who have PDS in the context of glaucoma and therapy with an intraocular-pressure-lowering agent may experience delayed healing and a less predictable visual outcome.
分析色素播散综合征（PDS）患者的准分子原位角膜磨镶术（LASIK）效果。
门诊流动激光视力矫正中心。
本非对照病例系列回顾了12例患者（22只眼）的病历，这些患者在初次术前屈光评估时具有与PDS一致的临床特征并接受了LASIK手术。
11例患者的20只眼（90.9%）LASIK术后过程顺利，最终裸眼视力良好（平均随访26个月）。1例接受局部β受体阻滞剂治疗、疑似青光眼的PDS患者（2只眼）愈合延迟，视力波动，视力恢复时间长。
PDS的角膜表现似乎不影响LASIK的术中或术后效果。然而，患有青光眼且正在使用降眼压药物治疗的PDS患者可能会出现愈合延迟和视力预后较难预测的情况。
