el-Ghazaly M, Khayyal M T, Okpanyi S N, Arens-Corell M
Pharmacology Department, Faculty of Pharmacy, Cairo University, Egypt.
Arzneimittelforschung. 1992 Mar;42(3):333-6.
Aqueous/alcoholic extracts of Populus tremula, Solidago virgaurea and Fraxinus excelsior (components of Phytodolor N) were tested individually and in 3 different combinations for anti-inflammatory activity using carrageenan induced edema and/or adjuvant induced arthritis of the rat paw. The tested combinations as well as the individual extracts significantly reduced the paw edema to varying degrees and also dose dependently inhibited the arthritic paw volume. The anti-inflammatory activity of the combinations was respectively comparable to the tested doses of diclofenac.
分别对欧洲山杨、金黄花一枝香和欧洲白蜡树(Phytodolor N的成分)的水/醇提取物进行了测试,并将其以3种不同组合用于大鼠足爪角叉菜胶诱导的水肿和/或佐剂诱导的关节炎,以检测其抗炎活性。所测试的组合以及单一提取物均不同程度地显著减轻了足爪水肿,并且还剂量依赖性地抑制了关节炎足爪的体积。这些组合的抗炎活性分别与所测试剂量的双氯芬酸相当。