Meyer B, Schneider W, Elstner E F
Steigerwald Arzneimittelwerk GmbH, Darmstadt, Germany.
Arzneimittelforschung. 1995 Feb;45(2):174-6.
Aqueous-ethanolic extracts from Fraxinus excelsior, Populus tremula and Solidago virgaurea inhibit biochemical model reactions representing inflammatory situations to various extents. These model reactions include xanthine oxidase, diaphorase in the presence of the autoxidizable quinone juglone, lipoxygenase and photodynamic reactions driven by riboflavin or rose bengal. The tested extracts are the components of the phytomedicine Phytodolor N (abbreviated as PD) which possesses antipyretic, analgesic, antiinflammatory and antirheumatic activity. Since several reactive oxygen species produced by the mentioned model systems are also involved in inflammatory processes, the beneficial activities of the complete drug may at least in part be due to the reported antioxidative functions of the individual components.
来自欧洲白蜡树、欧洲山杨和金黄花烛的水乙醇提取物在不同程度上抑制了代表炎症情况的生化模型反应。这些模型反应包括黄嘌呤氧化酶、在可自氧化醌胡桃醌存在下的黄递酶、脂氧合酶以及由核黄素或孟加拉玫瑰红驱动的光动力反应。所测试的提取物是植物药Phytodolor N（缩写为PD）的成分，该植物药具有解热、镇痛、抗炎和抗风湿活性。由于上述模型系统产生的几种活性氧也参与炎症过程，完整药物的有益活性可能至少部分归因于各成分所报道的抗氧化功能。
