Tranos P, Asaria R, Aylward W, Sullivan P, Franks W
Moorfields Eye Hospital, London, UK.
Br J Ophthalmol. 2004 Mar;88(3):341-3. doi: 10.1136/bjo.2003.028076.
To determine the long term outcome of secondary glaucoma following retinal reattachment surgery.
A longitudinal retrospective study was undertaken of the medical records of patients referred to the Glaucoma Service at Moorfields Eye Hospital following retinal reattachment surgery. The main outcome measures were final intraocular pressure (IOP), progression in cup:disc ratio, and final visual acuity outcome.
A total of 70 eyes of 70 patients (41 males and 29 females) were identified and included in the analysis. Mean increase of IOP 2-3 weeks following the first vitreoretinal procedure was 6 (SD 3) mm Hg. After a mean follow up of approximately 4 years the mean IOP had significantly decreased from 33 (SD 10) to 16 (SD 8) mm Hg (p<0.001). The visual outcome of eyes with final IOP less than 6 or greater than 21 mm Hg was significantly worse compared with those eyes with a normal (6-21 mm Hg) range of pressure (p = 0.022 and p = 0.009 respectively). Despite the effective control of IOP in the majority of patients during the follow up period, there was mild progression of the mean vertical cup:disc ratio from 0.6 (SD 0.2) to 0.7 (SD 0.2) (p<0.001).
Secondary glaucoma is a major complication following retinal reattachment surgery. Medical treatment is successful in lowering IOP in most patients. In persisting cases surgical treatment is very effective, however it can be associated with an increased risk of postoperative hypotony. Despite apparently adequate IOP control there may be progressive cupping of the optic disc.
确定视网膜复位手术后继发性青光眼的长期预后。
对 Moorfields 眼科医院青光眼服务部门接收的视网膜复位手术后患者的病历进行纵向回顾性研究。主要观察指标为最终眼压(IOP)、杯盘比进展情况及最终视力预后。
共纳入 70 例患者的 70 只眼(41 例男性和 29 例女性)进行分析。首次玻璃体视网膜手术后 2 - 3 周眼压平均升高 6(标准差 3)mmHg。平均随访约 4 年后,平均眼压从 33(标准差 10)显著降至 16(标准差 8)mmHg(p<0.001)。最终眼压低于 6 或高于 21 mmHg 的眼的视力预后明显差于眼压在正常范围(6 - 21 mmHg)的眼(分别为 p = 0.022 和 p = 0.009)。尽管在随访期间大多数患者的眼压得到有效控制,但平均垂直杯盘比仍有轻度进展,从 0.6(标准差 0.2)增至 0.7(标准差 0.2)(p<0.001)。
继发性青光眼是视网膜复位手术后的主要并发症。药物治疗在大多数患者中能成功降低眼压。对于持续存在的病例,手术治疗非常有效,但可能会增加术后低眼压的风险。尽管眼压控制看似充分,但视盘可能仍会逐渐凹陷。