Tuomilehto J, Dabee J, Karvonen M, Dowse G K, Gareeboo H, Virtala E, Tiihonen M, Alberti K G, Zimmet P Z
Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland.
Diabetes Care. 1993 Dec;16(12):1588-91. doi: 10.2337/diacare.16.12.1588.
To document the incidence of IDDM in Mauritian children and adolescents 0-19 yr of age from 1986 to 1990.
We used a population-based register that used pediatricians, physicians, nutritionists, and general practitioners as a primary source of retrospective case ascertainment. The denominator data were obtained from the Statistics Office of the Ministry of Health (Port Louis, Mauritius).
In 1990, 37 newly diagnosed IDDM cases (22 females and 15 males) were identified between 1986 and 1990 among the population < or = 19 yr of age. The average incidence density per year was 1.9/100,000 people and was slightly higher among girls (2.2/100,000) than among boys (1.5/100,000). The average age-standardized incidence density was 2.1/100,000 people (95% confidence interval 1.5-3.0) among children < or = 14 yr of age, 2.5/100,000 people (95% confidence interval 1.5-3.9) among girls, and 1.8/100,000 people (95% confidence interval 1.0-3.0) among boys. The incidence was similarly low in Mauritians of Asian Indian, Chinese, and Creole (predominantly African) origin.
The incidence of IDDM in Mauritian children and adolescents is among the lowest yet reported. This sharply contrasts with the very high risk of NIDDM found among the adult population in this rapidly modernizing country.
记录1986年至1990年毛里求斯0至19岁儿童及青少年中胰岛素依赖型糖尿病(IDDM)的发病率。
我们使用了一个基于人群的登记系统,以儿科医生、内科医生、营养师和全科医生作为回顾性病例确诊的主要来源。分母数据来自毛里求斯卫生部统计办公室(路易港)。
1990年,在19岁及以下人群中,1986年至1990年间共确诊37例新的IDDM病例(22例女性,15例男性)。每年的平均发病密度为1.9/100,000人,女孩(2.2/100,000)略高于男孩(1.5/100,000)。14岁及以下儿童的平均年龄标准化发病密度为2.1/100,000人(95%置信区间1.5 - 3.0),女孩为2.5/100,000人(95%置信区间1.5 - 3.9),男孩为1.8/100,000人(95%置信区间1.0 - 3.0)。亚洲印度裔、华裔和克里奥尔人(主要为非洲裔)毛里求斯人的发病率同样较低。
毛里求斯儿童及青少年中IDDM的发病率是已报道的最低发病率之一。这与这个快速现代化国家成年人群中发现的非胰岛素依赖型糖尿病(NIDDM)的高风险形成鲜明对比。