Beer Meinrad
Institute for Diagnostic Radiology, University Würzburg, Building 34, Josef-Schneider-Strasse 2, 97080 Würzburg, Germany.
Eur Radiol. 2004 Jun;14(6):1034-47. doi: 10.1007/s00330-004-2279-3. Epub 2004 Mar 6.
Cardiac MR spectroscopy allows the non-invasive assessment of metabolic processes. In contrast to numerous experimental applications, the clinical use of MRS is still restricted to specialized centers of expertise. However, during the last 10 years, several technical improvements as well as new clinical applications have been introduced, which might change this fact. This article focuses on (1) these recent technical advances such as reproducible quantification methods and dedicated data acquisition as well as postprocessing methods, (2) outlines emerging clinical indications and (3) summarizes available clinical studies. Basic principles of cardiac metabolism are presented, and discussed in the context of recent clinical papers. Finally, the impact of the new highest-field magnets--3 T and beyond--is discussed under the perspectives for the future clinical role of MR spectroscopy.
心脏磁共振波谱分析可对代谢过程进行无创评估。与众多实验应用不同,磁共振波谱分析的临床应用仍局限于专业的技术中心。然而,在过去十年中,已引入了多项技术改进以及新的临床应用,这可能会改变这一现状。本文重点关注:(1)这些最新的技术进展,如可重复的定量方法、专用的数据采集以及后处理方法;(2)概述新兴的临床适应症;(3)总结现有的临床研究。阐述了心脏代谢的基本原理,并结合近期临床论文进行了讨论。最后,从磁共振波谱分析未来临床作用的角度,讨论了新型高场强磁体(3T及以上)的影响。