Blattmann H
PSI Paul Scherrer Institute, Abteilung Strahlenmedizin, Villigen PSI, Switzerland.
Radiat Environ Biophys. 1992;31(3):219-31. doi: 10.1007/BF01214829.
Heavy charged particle therapy, started at research institutes three decades ago, is now on the verge of entering a clinical phase. This phase has resulted from the evolution and development of various beam delivery systems and techniques with existing research accelerators and with newly built accelerators. For the first thirty years, heavy charged particle therapy was administered with a fixed horizontal beam line. In 1991, the first treatment with an isocentric gantry was administered. The development of the isocentric gantry, the newest beam delivery system, and clearly a consequence of all the experience gained at the earlier facilities has many advantages. It offers advantageous physical properties of the particles as well as being equal in the flexibility of dose delivery to the modern photon radiotherapy gantries.
重离子治疗始于三十年前的研究机构,如今已步入临床阶段的边缘。这一阶段是各种束流传输系统和技术在现有研究加速器和新建加速器上不断演进和发展的结果。在最初的三十年里,重离子治疗是通过固定的水平束流线进行的。1991年,首次使用等中心机架进行治疗。等中心机架作为最新的束流传输系统,显然是早期设施积累的所有经验的成果,具有诸多优势。它不仅具备粒子的有利物理特性,而且在剂量输送的灵活性方面与现代光子放射治疗机架相当。