Bhattacharya S, Badrinath S, Hamide A, Sujatha S
Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry.
Indian J Pathol Microbiol. 2003 Jul;46(3):495-7.
Hepatitis C virus (HCV), which is usually transmitted by blood and blood products is emerging as an important agent in the list of sexually transmitted diseases (STDs). The present study was undertaken to document the burden of HCV infection in individuals with STDs in this tertiary care hospital in South India. One hundred serum samples collected from individuals with STDs were tested for antibodies to HCV by a third generation ELISA. All the samples were also screened for HIV infection. Six out of 100 individuals were found to possess antibodies against HCV (95% confidence interval [CI=1.3-10.7%). Fourteen out of 100 samples were positive for HIV (95% CI=7-20.9%). The seroprevalence of HCV in HIV positive individuals was 21.4% (3/14) whereas the corresponding figure for HIV negative individuals was only 3.5% (3/86). The difference was found to be statistically significant (p<0.01).
丙型肝炎病毒（HCV）通常通过血液及血液制品传播，正逐渐成为性传播疾病（STD）中的一种重要病原体。本研究旨在记录印度南部这家三级护理医院中感染性传播疾病个体的丙型肝炎病毒感染负担情况。从感染性传播疾病的个体中采集了100份血清样本，采用第三代酶联免疫吸附测定法检测丙型肝炎病毒抗体。所有样本还进行了HIV感染筛查。100名个体中有6人被发现具有抗丙型肝炎病毒抗体（95%置信区间[CI=1.3-10.7%]）。100份样本中有14份HIV检测呈阳性（95%CI=7-20.9%）。HIV阳性个体中丙型肝炎病毒的血清阳性率为21.4%（3/14），而HIV阴性个体的相应比例仅为3.5%（3/86）。发现差异具有统计学意义（p<0.01）。
