Lau Joseph T F, Fung Kitty S, Wong Tze Wai, Kim Jean H, Wong Eric, Chung Sidney, Ho Deborah, Chan Louis Y, Lui S F, Cheng Augustine
Centre for Epidemiology and Biostatistics, Faculty of Medicine, The Chinese University of Hong Kong, School of Public Health, Prince of Wales Hospital, Shatin, NT, Hong Kong Special Administrative Region, People's Republic of China.
Emerg Infect Dis. 2004 Feb;10(2):280-6. doi: 10.3201/eid1002.030534.
Despite infection control measures, breakthrough transmission of severe acute respiratory syndrome (SARS) occurred for many hospital workers in Hong Kong. We conducted a case-control study of 72 hospital workers with SARS and 144 matched controls. Inconsistent use of goggles, gowns, gloves, and caps was associated with a higher risk for SARS infection (unadjusted odds ratio 2.42 to 20.54, p < 0.05). The likelihood of SARS infection was strongly associated with the amount of personal protection equipment perceived to be inadequate, having <2 hours of infection control training, and not understanding infection control procedures. No significant differences existed between the case and control groups in the proportion of workers who performed high-risk procedures, reported minor protection equipment problems, or had social contact with SARS-infected persons. Perceived inadequacy of personal protection equipment supply, infection control training <2 hours, and inconsistent use of personal protection equipment when in contact with SARS patients were significant independent risk factors for SARS infection.
尽管采取了感染控制措施，但香港仍有许多医院工作人员出现严重急性呼吸综合征（SARS）的突破性传播。我们对72名感染SARS的医院工作人员和144名匹配的对照人员进行了一项病例对照研究。护目镜、隔离衣、手套和帽子使用不一致与SARS感染风险较高相关（未调整比值比为2.42至20.54，p<0.05）。SARS感染的可能性与被认为不足的个人防护装备数量、接受<2小时的感染控制培训以及不了解感染控制程序密切相关。在进行高风险操作、报告存在轻微防护装备问题或与感染SARS的人员有社交接触的工作人员比例方面，病例组和对照组之间没有显著差异。个人防护装备供应不足的认知、<2小时的感染控制培训以及接触SARS患者时个人防护装备使用不一致是SARS感染的重要独立危险因素。
