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香港医院医护人员中亚临床严重急性呼吸综合征相关冠状病毒感染的低患病率。

Low prevalence of subclinical severe acute respiratory syndrome-associated coronavirus infection among hospital healthcare workers in Hong Kong.

作者信息

Lai Thomas Sik To, Keung Ng Tak, Seto Wing Hong, Yam Loretta, Law Kin Ip, Chan Jane

机构信息

Department of Medicine, Princess Margaret Hospital, Lai Chi Kok, Kowloon, Hong Kong SAR, China.

出版信息

Scand J Infect Dis. 2005;37(6-7):500-3. doi: 10.1080/00365540510033645.


DOI:10.1080/00365540510033645
PMID:16012012
Abstract

We recruited 688 hospital healthcare workers who cared for patients with severe acute respiratory syndrome (SARS) and did not develop the disease in the Hong Kong outbreak in 2003. A questionnaire survey was conducted and serum samples were collected for SARS-associated coronavirus (SARS-CoV) antibody. The high-risk procedures performed and the types of unprotected exposures were recorded for analysis. Only 1 asymptomatic nurse had positive serological test. The result demonstrates the low rate of subclinical SARS-CoV infection in hospital healthcare workers and that the infection control practice against SARS in Hong Kong's hospitals during the outbreak was highly effective.

摘要

我们招募了688名在2003年香港严重急性呼吸系统综合症(SARS)疫情期间照顾SARS患者但未发病的医院医护人员。进行了问卷调查,并采集血清样本检测SARS相关冠状病毒(SARS-CoV)抗体。记录所执行的高风险操作和未受保护暴露的类型以供分析。只有1名无症状护士血清学检测呈阳性。结果表明医院医护人员中SARS-CoV亚临床感染率较低,且疫情期间香港医院针对SARS的感染控制措施非常有效。

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[2]
Personal protective equipment for preventing highly infectious diseases due to exposure to contaminated body fluids in healthcare staff.

Cochrane Database Syst Rev. 2020-5-15

[3]
Personal protective equipment for preventing highly infectious diseases due to exposure to contaminated body fluids in healthcare staff.

Cochrane Database Syst Rev. 2020-4-15

[4]
Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV).

Perspect Med Virol. 2006

[5]
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Cochrane Database Syst Rev. 2019-7-1

[6]
Personal protective equipment for preventing highly infectious diseases due to exposure to contaminated body fluids in healthcare staff.

Cochrane Database Syst Rev. 2016-4-19

[7]
The lessons of SARS in Hong Kong.

Clin Med (Lond). 2010-2

[8]
Duration and distance of exposure are important predictors of transmission among community contacts of Ontario SARS cases.

Epidemiol Infect. 2007-8

[9]
Extremely low exposure of a community to severe acute respiratory syndrome coronavirus: false seropositivity due to use of bacterially derived antigens.

J Virol. 2006-9

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