Guihot Amélie, Bricaire François, Li Taisheng, Bossi Philippe
Service de maladies infectieuses et tropicales, hôpital Pitié-Salpêtrière, Paris.
Presse Med. 2004 Mar 13;33(5):344-51. doi: 10.1016/s0755-4982(04)98581-8.
INFECTIOUS AGENT: The severe acute respiratory syndrome (SARS) is a febrile pneumonia initially observed in China at the end of 2002. The infectious agent has rapidly been identified as a new coronavirus, baptised SARS-associated coronavirus (CoV-SARS). Transmission is inter-human, via respiratory particles mainly.
The clinical presentation is highly variable, from a mild fever to an acute respiratory distress syndrome. There is no specific treatment. Ribavirin associated with steroids have been used with success in numerous cases.
During the first half of 2003, the spreading of the virus has been very fast, with a pandemic mode of evolution. More than 8,000 people were infected and 774 died. The reservoir of the virus, which may be animal, is still unknown. The epidemic seems to be controlled, but sporadic or epidemic re-emergences may occur and have been observed in China during January 2004.
感染源:严重急性呼吸综合征(SARS)是一种发热性肺炎,2002年底首次在中国发现。感染源很快被确定为一种新型冠状病毒,命名为SARS相关冠状病毒(CoV-SARS)。传播途径主要是人际间通过呼吸道飞沫传播。
临床表现差异很大,从轻度发热到急性呼吸窘迫综合征。没有特效治疗方法。利巴韦林联合类固醇在许多病例中取得了成功。
2003年上半年,病毒传播非常迅速,呈大流行态势。超过8000人感染,774人死亡。病毒的储存宿主可能是动物,目前仍不清楚。疫情似乎已得到控制,但在中国2004年1月期间仍有散发病例或疫情再次出现。