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老年人的眼部变化、眼部疾病风险标志物及白内障手术的影响:一项对瑞典城市人群从70岁至97岁的随访研究。

Ocular changes, risk markers for eye disorders and effects of cataract surgery in elderly people: a study of an urban Swedish population followed from 70 to 97 years of age.

作者信息

Bergman Birgitta, Nilsson-Ehle Herman, Sjöstrand Johan

机构信息

Department of Ophthalmology, Institute of Clinical Neuroscience, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.

出版信息

Acta Ophthalmol Scand. 2004 Apr;82(2):166-74. doi: 10.1111/j.1600-0420.2004.00182.x.

Abstract

AIMS

To investigate the prevalence of and potential risk factors for ocular disorders and the effects of timing of cataract surgery from age 70-97 years.

POPULATION

A representative population sample taken from within the Gerontological and Geriatric Population Studies (H 70) in Gothenburg, Sweden (n = 958). All subjects underwent eye examinations at age 70 years in 1971 and subsequently at ages 82, 88, 95 and 97 years. All inhabitants of Gothenburg aged 95 and 97 years were invited to participate in the study.

RESULTS

Decreased vision (visual acuity < or = 0.5) was found in 20% and 80% of subjects at ages 82 and 97 years, respectively. Blood folate and physical activity at age 70 years correlated positively and body mass index (BMI) negatively to visual acuity (VA) > or = 0.8 at ages 82 and 88 years. Smoking at age 70 years correlated to early age-related maculopathy (ARM). Cataract surgery had been performed in 40% of subjects at age 97 years. Surgery 2 years earlier led to a 15% increase in time spent with improved vision.

CONCLUSIONS

The deterioration of vision in elderly people is a major health problem, for which 'low' folate status, smoking, 'high' BMI and low physical activity are potential risk factors. Early cataract surgery is also beneficial in very old patients.

摘要

目的

调查70至97岁人群眼部疾病的患病率及潜在风险因素,以及白内障手术时机的影响。

研究对象

从瑞典哥德堡老年人口研究(H70)中选取的具有代表性的人群样本(n = 958)。所有受试者于1971年70岁时接受了眼部检查,随后在82岁、88岁、95岁和97岁时再次接受检查。邀请了哥德堡所有95岁和97岁的居民参与该研究。

结果

分别在82岁和97岁的受试者中,发现视力下降(视力≤0.5)的比例为20%和80%。70岁时的血液叶酸水平和身体活动与82岁和88岁时视力≥0.8呈正相关,而体重指数(BMI)与之呈负相关。70岁时吸烟与早期年龄相关性黄斑病变(ARM)相关。97岁时40%的受试者接受了白内障手术。提前2年进行手术可使视力改善的时间增加15%。

结论

老年人视力下降是一个主要的健康问题,“低”叶酸水平、吸烟、“高”BMI和低身体活动是潜在的风险因素。早期白内障手术对高龄患者也有益。

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