Táborský L, Adam P, Sobek O, Dostál M, Dvoráková J, Dubská L
Department of Clinical Biochemistry, Hospital Homolka, 150 30 Prague, Czechia.
Folia Microbiol (Praha). 2003;48(6):849-55. doi: 10.1007/BF02931523.
Levels of most of the examined proteins in cerebrospinal fluid (CSF) of 107 patients with neuroborreliosis were associated with cytological findings, the status of hematoencephalic barrier as evaluated by Qalb (cerebrospinal fluid to serum quotient) and the intrathecal synthesis of immunoglobulins. Cytological findings consisted of normal cytology, or both oligocytosis and pleocytosis of monocytes or lymphocytes. The lipophagic elements were present in 20% of samples. Concentrations of apolipoproteins A-I and A-II in the CSF were correlated with the concentration of albumin without regard to the CSF cytology. The levels of apolipoprotein B were increased only in samples with lymphocytic pleocytosis and Qalb > 7.4. The presence of lipophages in the CSF was significantly associated with the CSF concentration of apolipoprotein A-II.
107例神经莱姆病患者脑脊液（CSF）中大多数检测蛋白的水平与细胞学检查结果、通过Qalb（脑脊液与血清商）评估的血脑屏障状态以及免疫球蛋白的鞘内合成有关。细胞学检查结果包括正常细胞学，或单核细胞或淋巴细胞的少细胞增多症和多细胞增多症。20%的样本中存在噬脂成分。脑脊液中载脂蛋白A-I和A-II的浓度与白蛋白浓度相关，而与脑脊液细胞学无关。仅在淋巴细胞增多症且Qalb>7.4的样本中载脂蛋白B水平升高。脑脊液中噬脂细胞的存在与脑脊液中载脂蛋白A-II的浓度显著相关。
