Azizian Javad, Karimi Ali R, Arefrad Hamedeh, Mohammadi Ali A, Mohammadizadeh M R
Department of Chemistry, Faculty of Science, Shahid Beheshti University, Tehran, Iran.
Mol Divers. 2003;6(3-4):223-6. doi: 10.1023/b:modi.0000006779.13561.12.
A new one-pot four component procedure for synthesis of densely functionalized pyrroles using commercially available ninhydrin with phosphorane intermediates produced in the reaction between triphenylphosphine, ammonium thiocyanate (or ammonium acetate) and various dialkyl acetylenedicarboxylates was developed.
开发了一种新的一锅四组分方法,该方法使用市售茚三酮与三苯基膦、硫氰酸铵(或乙酸铵)和各种二烷基乙炔二羧酸酯之间反应生成的磷叶立德中间体来合成高度官能化的吡咯。