Mullins Mark E, Lev Michael H, Bove Peter, O'Reilly Cara E, Saini Sanjay, Rhea James T, Thrall James H, Hunter George J, Hamberg Leena M, Gonzalez R Gilberto
Neuroradiology Division, Massachusetts General Hospital and the Harvard Medical School, Boston, MA, USA.
AJNR Am J Neuroradiol. 2004 Apr;25(4):533-8.
Increasing use of CT for evaluating neurologic disease may expose patients to considerable levels of ionizing radiation. We compared the image quality of low-mAs head CT scans with that of conventional nonenhanced scans.
Conventional head CT scans were obtained in 20 patients (all >65 years with history of non-CNS malignancy) by using a multidetector technique: 170 mA and 1-second scanning time (ie, 170 mAs), 140 kVp, table speed of 7.5 mm per rotation, pitch of 0.75, section thickness of 5 mm, and field of view of 25 mm. A limited volume helical data acquisition covering four 5-mm-thick images was obtained by using 90 mAs but otherwise the same parameters. Three neuroradiologists visually rated the resulting images for quality in a blinded comparison. Representative 1- to 4-mm(2) regions of interest were chosen in gray matter and white matter locations. Conspicuity and the contrast-to-noise ratio were analyzed. Statistical comparisons were done by using the Student t test.
Mean gray matter conspicuity was not significantly different between the 170- and 90-mAs groups (0.39 +/- 0.19 vs 0.41 +/- 0.03, P =.32). Mean gray matter contrast-to-noise ratio was approximately 22% higher with 170 mAs than with 90 mAs (1.77 +/- 0.52 vs 1.39 +/- 0.38, P =.005). All 90-mAs images were rated as having slightly greater image noise than the 170-mAs scans but with sufficient perceived resolution.
Although 90-mAs head CT images were moderately noisier than 170-mAs images, they were rated as having acceptable diagnostic quality.
越来越多地使用CT来评估神经系统疾病可能会使患者暴露于相当水平的电离辐射中。我们比较了低毫安秒头部CT扫描与传统非增强扫描的图像质量。
对20例患者(均为年龄大于65岁且有非中枢神经系统恶性肿瘤病史者)采用多探测器技术进行传统头部CT扫描:170毫安、1秒扫描时间(即170毫安秒)、140千伏峰值、每旋转7.5毫米的床速、0.75的螺距、5毫米的层厚以及25毫米的视野。通过使用90毫安秒获取覆盖四张5毫米厚图像的有限容积螺旋数据采集,其他参数相同。三位神经放射科医生在双盲比较中对所得图像的质量进行视觉评分。在灰质和白质位置选择代表性的1至4平方毫米的感兴趣区域。分析了清晰度和对比噪声比。采用Student t检验进行统计学比较。
170毫安秒组与90毫安秒组之间的平均灰质清晰度无显著差异(0.39±0.19对0.41±0.03,P = 0.32)。170毫安秒时的平均灰质对比噪声比比90毫安秒时约高22%(1.77±0.52对1.39±0.38,P = 0.005)。所有90毫安秒的图像被评为比170毫安秒的扫描图像噪声略大,但具有足够的可感知分辨率。
尽管90毫安秒的头部CT图像比170毫安秒的图像噪声稍大,但它们被评为具有可接受的诊断质量。