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氧化应激与阿尔茨海默病的风险因素:预防与治疗的线索

Oxidative stress and risk factors for Alzheimer's disease: clues to prevention and therapy.

作者信息

Polidori M Cristina

机构信息

Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, Universitätsstr. 1, D-40225 Düsseldorf, Germany.

出版信息

J Alzheimers Dis. 2004 Apr;6(2):185-91. doi: 10.3233/jad-2004-6211.

DOI:10.3233/jad-2004-6211
PMID:15096703
Abstract

The protective role of antioxidants against the development of several diseases and conditions recognized as risk factors for Alzheimer's disease (AD) is discussed in the present work. A variety of health behaviors, including an adequate supply of antioxidant micronutrients with the diet might help preventing AD directly, or indirectly through the mitigation of pathologic conditions associated with AD, such as vascular disease and diabetes.

摘要

本研究探讨了抗氧化剂对几种被认为是阿尔茨海默病(AD)风险因素的疾病和状况发展的保护作用。多种健康行为,包括通过饮食充足供应抗氧化微量营养素,可能有助于直接预防AD,或通过减轻与AD相关的病理状况(如血管疾病和糖尿病)间接预防AD。

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