Suppr超能文献

饮用水微生物污染与消毒副产物(DBPs)的风险分析

Risk analysis of drinking water microbial contamination versus disinfection by-products (DBPs).

作者信息

Ashbolt Nicholas John

机构信息

CRC for Water Quality and Treatment, School of Civil and Environmental Engineering, UNSW, Sydney, NSW 2052, Australia.

出版信息

Toxicology. 2004 May 20;198(1-3):255-62. doi: 10.1016/j.tox.2004.01.034.

Abstract

Managing the provision of safe drinking water has a renewed focus in light of the new World Health Organization (WHO) water safety plans. Risk analysis is a necessary component to assist in selecting priority hazards and identifying hazardous scenarios, be they qualitative to quantitative assessments. For any approach, acute diarrhoeal pathogens are often the higher risk issue for municipal water supplies, no matter how health burden is assessed. Furthermore, potential sequellae (myocarditis, diabetes, reactive arthritis and cancers) only further increase the potential health burden of pathogens; despite the enormous uncertainties in determining pathogen exposures and chemical dose-responses within respective microbial and chemical analyses. These interpretations are currently being improved by Bayesian and bootstrapping approaches to estimate parameters for stochastic assessments. A case example, covering the health benefits of ozonation for Cryptosporidium inactivation versus potential cancers from bromate exposures, illustrated the higher risks from a pathogen than one of the most likely disinfection by-products (DBPs). Such analyses help justify the industries long-held view of the benefits of multiple barriers to hazards and that microbial contamination of water supplies pose a clear public health risk when treatment is inadequate. Therefore, efforts to reduce potential health risks from DBP must not compromise pathogen control, despite socio-political issues.

摘要

鉴于世界卫生组织(WHO)新的水安全计划,安全饮用水供应管理有了新的重点。风险分析是协助选择优先危害和识别危险场景的必要组成部分,无论是定性评估还是定量评估。对于任何方法,急性腹泻病原体通常是城市供水的较高风险问题,无论健康负担如何评估。此外,潜在的后遗症(心肌炎、糖尿病、反应性关节炎和癌症)只会进一步增加病原体的潜在健康负担;尽管在各自的微生物和化学分析中确定病原体暴露和化学剂量反应存在巨大的不确定性。目前,贝叶斯方法和自举法正在改进这些解释,以估计随机评估的参数。一个案例,涵盖了臭氧灭活隐孢子虫的健康益处与溴酸盐暴露导致潜在癌症的比较,说明了病原体带来的风险高于最可能的消毒副产物(DBP)之一。此类分析有助于证明行业长期以来对多重危害屏障益处的看法,以及当处理不当时供水微生物污染会带来明显的公共卫生风险。因此,尽管存在社会政治问题,但降低DBP潜在健康风险的努力绝不能损害病原体控制。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验