Soderstrom H, Forsman A
National Board of Forensic Medicine, Department of Forensic Psychiatry, Göteborg, Sweden.
J Neural Transm (Vienna). 2004 Jun;111(6):739-44. doi: 10.1007/s00702-004-0137-8. Epub 2004 Apr 8.
We assessed a total range of peripheral thyroid hormone fractions, binding globulins, and thyroid-active antibodies in 37 medication-free, violent or sexual offenders, aged 17-45 years, to describe possible mechanisms involved in the thyroid metabolism of aggressive men. The ratio between T3 and T4 correlated with ratings of psychopathy, indicating increased peripheral deiodination as a biological covariate to callous personality traits. Autoimmune antibodies, hepatic failure, abnormal binding globulins, or substance abuse did not affect the association.
