Acar Hasan, Ulgen Ayse
Girne American University Medical Faculty, Karmi, Cyprus.
Int J Endocrinol. 2020 Mar 9;2020:9172134. doi: 10.1155/2020/9172134. eCollection 2020.
Various factors cause aggression, which can be related to imbalance of T3 and T4 hormones, which can act as neurotransmitters and are reported to be elevated during aggression. This indicates changes in the hypothalamic-pituitary-thyroid axis that cause long-term changes in aggressive behaviour, especially in criminals. Moreover, mental and behavioural disorders possibly occur in individuals with impairment in thyroid hormone balance. The main rationale for this study was to asses if high T3, high T4, and low TSH hormones may have an effect on aggression-related crime tendency. Furthermore, the study aimed to measure levels of thyroid hormones in prisoners and to examine relationships of the hormone levels with crime rates. Our study was conducted in Ankara Sincan Closed Prisons. The study group consisted of 208 male volunteers who were imprisoned and the control group included 82 male volunteers who were not imprisoned. Prisoners in the study group were divided into two groups: those who committed aggression-related crime (Group A, = 96) and prisoners convicted of other crimes (Group B, = 112). Pulse rates, T3, T4, and thyroid-stimulating hormone (TSH) levels, and theT3/T4 ratio were measured in these prisoners. Data were analysed using the Wilcoxon rank sum test and chi-square Fisher's exact test to test for any statistically significant differences. Results showed that toxic goitre rates, T3 and T4 values, and pulse rates were significantly higher in Group A than in the control group. Significant increase in T3 and T4 levels and the presence of toxic goitre were associated with aggression-related crime. These examinations should be performed on prisoners in general, especially those convicted of violent crimes. Additional rehabilitation and research programs should also be developed for such patients.
多种因素会导致攻击行为，这可能与T3和T4激素失衡有关，这两种激素可充当神经递质，据报道在攻击行为发生时会升高。这表明下丘脑 - 垂体 - 甲状腺轴发生了变化，导致攻击行为出现长期改变，尤其是在罪犯中。此外，甲状腺激素平衡受损的个体可能会出现精神和行为障碍。本研究的主要目的是评估高T3、高T4和低促甲状腺激素（TSH）激素是否可能对与攻击相关的犯罪倾向产生影响。此外，该研究旨在测量囚犯体内甲状腺激素的水平，并检查激素水平与犯罪率之间的关系。我们的研究在安卡拉辛坎封闭式监狱进行。研究组由208名被监禁的男性志愿者组成，对照组包括82名未被监禁的男性志愿者。研究组中的囚犯被分为两组：实施与攻击相关犯罪的囚犯（A组，n = 96）和被判犯有其他罪行的囚犯（B组，n = 112）。测量了这些囚犯的脉搏率、T3、T4和促甲状腺激素（TSH）水平以及T3/T4比值。使用Wilcoxon秩和检验和卡方费舍尔精确检验分析数据，以检验是否存在任何统计学上的显著差异。结果显示，A组的毒性甲状腺肿发生率、T3和T4值以及脉搏率均显著高于对照组。T3和T4水平的显著升高以及毒性甲状腺肿的存在与与攻击相关的犯罪有关。一般应对囚犯进行此类检查，尤其是那些被判犯有暴力罪行的囚犯。还应为这类患者制定额外的康复和研究计划。
