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腹泻期间在家中进行母乳喂养和口服补液以预防脱水。

Breast feeding and oral rehydration at home during diarrhoea to prevent dehydration.

作者信息

Faruque A S, Mahalanabis D, Islam A, Hoque S S, Hasnat A

机构信息

International Centre for Diarrhoeal Disease Research, Bangladesh.

出版信息

Arch Dis Child. 1992 Aug;67(8):1027-9. doi: 10.1136/adc.67.8.1027.

Abstract

In a case-control study we evaluated the role of maternal behaviour, as reflected in maintenance of breast feeding and the use of oral rehydration therapy (ORT) at home during acute diarrhoea, in preventing dehydration in infants and young children. A systematic 5% sample was taken of all children aged 1-35 months attending the treatment centre of the International Centre for Diarrhoeal Disease Research, Bangladesh, with acute watery diarrhoea of six days or less between August 1988 and September 1989. There were 285 children with moderate or severe dehydration as cases and 728 with no dehydration as controls in the study. In a multivariate analysis using a logistic regression model we showed that withdrawal of breast feeding during diarrhoea was associated with a five times higher risk of dehydration compared with continuation of breast feeding during diarrhoea at home. Lack of ORT with either complete formula or a salt and sugar solution at home was associated with 57% higher risk of dehydration compared with receipt of a reasonable amount of ORT after controlling for several confounders. The confounding variables--that is, lack of maternal education, history of vomiting, high stool frequency, young age and infection with Vibrio cholerae 01--were also shown to be risk factors of dehydration. Health education programmes should promote continued breast feeding and adequate oral rehydration therapy for infants with acute diarrhoea at home.

摘要

在一项病例对照研究中,我们评估了母亲行为在预防婴幼儿脱水方面所起的作用,这些行为体现在母乳喂养的持续情况以及急性腹泻期间在家中使用口服补液疗法(ORT)上。对1988年8月至1989年9月期间在孟加拉国腹泻病研究国际中心治疗中心就诊的所有1至35个月大患有急性水样腹泻且病程不超过6天的儿童,系统抽取了5%的样本。该研究中,有285名患有中度或重度脱水的儿童作为病例,728名未脱水的儿童作为对照。在使用逻辑回归模型的多变量分析中,我们发现腹泻期间停止母乳喂养与腹泻期间在家继续母乳喂养相比,脱水风险高出五倍。在控制了几个混杂因素后,在家中未使用完全配方奶或盐糖溶液进行口服补液疗法与接受适量口服补液疗法相比,脱水风险高出57%。混杂变量,即母亲受教育程度低、呕吐史、高粪便频率、年龄小以及感染霍乱弧菌01,也被证明是脱水的危险因素。健康教育项目应促进急性腹泻婴儿在家中持续母乳喂养和进行充分的口服补液疗法。

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