De Schaepdrijver L, Simoens P, Pollet L, Lauwers H, De Laey J J
Laboratory of Anatomy, Histology and Embryology of Domestic Animals, Faculty of Veterinary Medicine, State University of Ghent, Belgium.
Exp Eye Res. 1992 Jun;54(6):975-85. doi: 10.1016/0014-4835(92)90162-l.
The retinal blood circulation was examined in 20 porcine eyes by studying fluoangiograms before and after occlusion of the temporal choroidal circulation. The use of a small intravenous bolus of 2.5 ml fluorescein provided high-resolution angiograms with detailed information of the retinal vascular bed. The lobular filling pattern of the choriocapillaris very closely resembles the human pattern. The intrinsic retinal vasculature of the miniature pig also has numerous characteristics in common with the human retina with regard to the extent of the vascular bed, the size of the blood vessels and the presence of radial peridiscal capillaries. Unlike the central fovea in the human eye, the porcine retina has a streak-like macular area which extends both temporally and nasally and which, although it is free of major blood vessels, is not completely avascular. This fluoangiographic study substantiates the results of the accompanying paper. It may be concluded that the miniature pig is a suitable experimental animal for applied research on the retinal vasculature.
通过研究颞侧脉络膜循环阻塞前后的荧光血管造影，对20只猪眼的视网膜血液循环进行了检查。静脉注射2.5毫升小剂量荧光素可提供高分辨率血管造影，显示视网膜血管床的详细信息。脉络膜毛细血管的小叶状充盈模式与人类模式非常相似。小型猪的视网膜固有血管系统在血管床范围、血管大小和放射状视盘周围毛细血管的存在方面也有许多与人类视网膜相同的特征。与人类眼睛的中央凹不同，猪视网膜有一个条纹状的黄斑区，向颞侧和鼻侧延伸，虽然没有主要血管，但并非完全无血管。这项荧光血管造影研究证实了随附论文的结果。可以得出结论，小型猪是用于视网膜血管系统应用研究的合适实验动物。
