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小型猪眼底荧光血管造影的麻醉

Anaesthesia for fluorescein angiography of the ocular fundus in the miniature pig.

作者信息

Gasthuys F, Pollet L, Simoens P, Lauwers H, De Laey J J

机构信息

Large Animal Surgical Clinic, Faculty of Veterinary Medicine, State University of Ghent, Belgium.

出版信息

Vet Res Commun. 1990;14(5):393-402. doi: 10.1007/BF00343217.

DOI:10.1007/BF00343217
PMID:2247945
Abstract

A safe and reproducible procedure is described for anaesthesia and ophthalmic fluorescein angiography in the miniature pig. Twenty examinations were performed in five adult miniature pigs. A detailed description is given of the anaesthetic procedure, in particular of the techniques for endotracheal intubation and for intra-arterial and intravenous cannulation. All cardiovascular parameters recorded during the experiments remained within acceptable anaesthetic limits. The fluorescein angiographic technique, which is routinely used in human ophthalmology, was adapted for the pig. This procedure for in vivo examination of the porcine eye is interesting and useful for experimental ophthalmic research.

摘要

本文描述了一种用于小型猪麻醉和眼科荧光血管造影的安全且可重复的方法。对五只成年小型猪进行了二十次检查。文中详细描述了麻醉过程,特别是气管插管以及动脉和静脉插管技术。实验过程中记录的所有心血管参数均保持在可接受的麻醉范围内。常规用于人类眼科的荧光血管造影技术已适用于猪。这种用于猪眼活体检查的方法对实验性眼科研究具有重要意义且十分有用。

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本文引用的文献

1
Fluorescein angiography of the choroid in health and disease.健康与疾病状态下脉络膜的荧光素血管造影
Int Ophthalmol. 1983 Feb;6(2):125-38. doi: 10.1007/BF00127641.
2
I. Ophthalmoscopic and circulatory changes in focal retinal ischaemia.I. 局灶性视网膜缺血的检眼镜及循环变化
Br J Ophthalmol. 1966 Jun;50(6):285-324. doi: 10.1136/bjo.50.6.285.
3
Retinal vasculature of the pig. Light and electron microscope studies.猪的视网膜血管系统。光镜和电镜研究。
Exp Eye Res. 1965 Sep;4(3):174-8. doi: 10.1016/s0014-4835(65)80029-x.
4
Effect of raised intraocular pressure on the retinal and choroidal circulation.眼压升高对视网膜和脉络膜循环的影响。
Invest Ophthalmol. 1968 Apr;7(2):191-8.
5
Experimental retinal branch vein occlusion.实验性视网膜分支静脉阻塞
Am J Ophthalmol. 1970 May;69(5):778-825. doi: 10.1016/0002-9394(70)93420-3.
6
Recent advances in fluorescein fundus angiography.荧光素眼底血管造影术的最新进展
Br J Ophthalmol. 1974 Apr;58(4):391-412. doi: 10.1136/bjo.58.4.391.
7
Fluoro-angiographic study of the choroid in man.人体脉络膜的荧光血管造影研究。
Bull Soc Belge Ophtalmol. 1977;174:III-VII, 1-217.