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新型阴道润滑剂Astroglide的评估:暴露时间和浓度对精子活力的影响

Evaluation of Astroglide, a new vaginal lubricant: effects of length of exposure and concentration on sperm motility.

作者信息

Frishman G N, Luciano A A, Maier D B

机构信息

Department of Obstetrics and Gynecology, University of Connecticut, Farmington.

出版信息

Fertil Steril. 1992 Sep;58(3):630-2.

PMID:1521661
Abstract

Traditional vaginal lubricants have been shown to adversely affect sperm motility. Astroglide, a new vaginal lubricant, and K-Y Jelly were tested at varying concentrations to assess their suitability for infertility patients requiring a lubricant. The vaginal lubricants tested impaired sperm motility in a concentration-dependent but not time-dependent manner. We conclude that all traditional vaginal lubricants should be avoided in patients desiring conception. Future studies should attempt to mimic in vivo conditions and focus on concentration-dependent effects.

摘要

传统阴道润滑剂已被证明会对精子活力产生不利影响。对一种新型阴道润滑剂Astroglide和K-Y凝胶进行了不同浓度的测试,以评估它们对需要润滑剂的不孕患者的适用性。所测试的阴道润滑剂以浓度依赖性而非时间依赖性方式损害精子活力。我们得出结论,希望受孕的患者应避免使用所有传统阴道润滑剂。未来的研究应尝试模拟体内条件,并关注浓度依赖性效应。

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