Khan Farhad Ali, Zia Elisabet, Janzon Lars, Engstrom Gunnar
Department of Community Medicine, Malmö University Hospital, Malmö, Sweden.
Stroke. 2004 Sep;35(9):2054-8. doi: 10.1161/01.STR.0000135761.18954.0b. Epub 2004 Jul 1.
The proportion of immigrants has increased in Sweden markedly during the last decades, as in many other Western countries. Incidence of stroke has increased during this period. However, it is primarily unknown whether incidence of stroke and stroke subtypes in Sweden is related to country of birth.
Incidence of first-ever stroke was followed during 10 years in a cohort consisting of all 40- to 89-year-old inhabitants in the city of Malmö, Sweden (n=118,134). Immigrants from 12 different countries were compared with native-born Swedes.
Adjusted for age, sex, marital status, and socioeconomic indicators, the incidence of stroke (all subtypes) was significantly higher among immigrants from former Yugoslavia (relative risk [RR], 1.31; 95% CI, 1.1 to 1.6) and Hungary (RR, 1.33; CI, 1.02 to 1.7). A significantly increased incidence of intracerebral hemorrhage was observed in immigrants from Peoples Republic of China or Vietnam (RR, 4.2; CI, 1.7 to 10.4) and the former Soviet Union (RR, 2.7; CI, 1.01 to 7.3). Immigrants from Finland had a significantly higher incidence of subarachnoid hemorrhage (RR, 2.8; CI, 1.1 to 6.8). A significantly lower incidence of stroke was observed in the group from Romania (RR, 0.14; CI, 0.04 to 0.6). Immigrants from Denmark, Norway, Germany, Chile, Czechoslovakia, and Poland had approximately the same risk as citizens born in Sweden.
In this urban population from Sweden, there are substantial differences in stroke incidence and stroke subtypes between immigrants from different countries. To what extent this could be accounted for by exposure to biological risk factors remains to be explored.
在过去几十年里，瑞典的移民比例显著增加，许多其他西方国家亦是如此。在此期间，中风的发病率有所上升。然而，瑞典中风及中风亚型的发病率是否与出生国相关，目前主要仍不清楚。
对瑞典马尔默市所有40至89岁居民组成的队列（n = 118,134）进行了为期10年的首次中风发病率跟踪研究。将来自12个不同国家的移民与瑞典本土出生的人进行了比较。
在对年龄、性别、婚姻状况和社会经济指标进行调整后，来自前南斯拉夫的移民（相对风险[RR]，1.31；95%置信区间[CI]，1.1至1.6）和匈牙利的移民（RR，1.33；CI，1.02至1.7）中中风（所有亚型）的发病率显著更高。在中国或越南的移民（RR，4.2；CI，1.7至10.4）以及前苏联的移民（RR，2.7；CI，1.01至7.3）中观察到脑出血的发病率显著增加。来自芬兰的移民蛛网膜下腔出血的发病率显著更高（RR，2.8；CI，1.1至6.8）。罗马尼亚组的中风发病率显著较低（RR，0.14；CI，0.04至0.6）。来自丹麦、挪威、德国、智利、捷克斯洛伐克和波兰的移民与瑞典出生的公民风险大致相同。
在瑞典的这一城市人口中，不同国家的移民在中风发病率和中风亚型方面存在显著差异。这在多大程度上可归因于接触生物危险因素仍有待探索。
