Hedlund Ebba, Lange Anders, Hammar Niklas
Department of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Eur J Epidemiol. 2007;22(8):493-503. doi: 10.1007/s10654-007-9147-9. Epub 2007 Jul 18.
This study investigates incidence of first acute myocardial infarction (MI) among foreign born persons in Sweden using case control methods, taking into consideration country of birth, gender, socio-economic group and time since immigration and evaluates if the decreasing incidence of MI in Sweden during the study period was also present in immigrants. The study base consisted of persons 30-74 years of age in Stockholm County 1977-96. All incident cases of first acute MI in the study population were identified using registers of hospital discharges and deaths. Controls were selected randomly from the study base and the sampling fractions were known, enabling estimates of person time at risk. Foreign born subjects had a higher incidence of MI than subjects born in Sweden (men RR[Relative risk]=1,17; 95% CI 1,13-1,21; women RR = 1,15; 95% CI 1,09-1,21) after adjustment for calendar year, age and socio-economic group. An increased incidence was present primarily in subjects born in Finland, other Nordic countries, Poland, Turkey, Syria and South Asia in both genders, from the Netherlands among men and from Iraq among women and was still present after more than 20 years in Sweden. The incidence rate of MI 1977-96 among foreign born persons followed the general decline in the Swedish population. We conclude that foreign born persons in Sweden have an increased incidence of first MI which persists several years after immigration and is not explained by socio-economic differences. It is likely that this to an important extent has a background in factors in the country of origin.
本研究采用病例对照方法,调查瑞典外国出生人群中首次急性心肌梗死(MI)的发病率,同时考虑出生国家、性别、社会经济群体以及移民后的时间,并评估在研究期间瑞典MI发病率的下降趋势在移民中是否也存在。研究对象为1977 - 1996年斯德哥尔摩县30 - 74岁的人群。通过医院出院和死亡登记册确定研究人群中所有首次急性MI的发病病例。从研究对象中随机选取对照,抽样比例已知,从而能够估计风险人时。在对历年、年龄和社会经济群体进行调整后,外国出生的受试者MI发病率高于瑞典出生的受试者(男性相对风险[RR]=1.17;95%置信区间[CI]为1.13 - 1.21;女性RR = 1.15;95% CI为1.09 - 1.21)。发病率增加主要出现在出生于芬兰、其他北欧国家、波兰、土耳其、叙利亚和南亚的男女受试者中,男性中来自荷兰的受试者以及女性中来自伊拉克的受试者也有增加,且在瑞典居住超过20年后仍存在这种情况。1977 - 1996年外国出生人群中MI的发病率随瑞典总体人群呈下降趋势。我们得出结论,瑞典外国出生人群首次MI的发病率增加,在移民后数年持续存在且无法用社会经济差异来解释。这很可能在很大程度上源于原籍国的因素。