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Tips for learners of evidence-based medicine: 1. Relative risk reduction, absolute risk reduction and number needed to treat.

作者信息

Barratt Alexandra, Wyer Peter C, Hatala Rose, McGinn Thomas, Dans Antonio L, Keitz Sheri, Moyer Virginia, For Gordon Guyatt

机构信息

School of Public Health, University of Sydney, Sydney, Australia.

出版信息

CMAJ. 2004 Aug 17;171(4):353-8. doi: 10.1503/cmaj.1021197.

DOI:10.1503/cmaj.1021197
PMID:15313996
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC509050/
Abstract
摘要

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本文引用的文献

1
Tips for learning and teaching evidence-based medicine: introduction to the series.循证医学学习与教学小贴士：系列介绍
CMAJ. 2004 Aug 17;171(4):347-8. doi: 10.1503/cmaj.1031665.
2
Can we individualize the 'number needed to treat'? An empirical study of summary effect measures in meta-analyses.我们能否使“需治疗人数”个体化？一项关于荟萃分析中汇总效应量的实证研究。
Int J Epidemiol. 2002 Feb;31(1):72-6. doi: 10.1093/ije/31.1.72.
3
When should an effective treatment be used? Derivation of the threshold number needed to treat and the minimum event rate for treatment.何时应使用有效治疗方法？治疗所需阈值数量和治疗最小事件发生率的推导。
J Clin Epidemiol. 2001 Mar;54(3):253-62. doi: 10.1016/s0895-4356(01)00347-x.
4
An empirical study of the effect of the control rate as a predictor of treatment efficacy in meta-analysis of clinical trials.在临床试验的荟萃分析中，将控制率作为治疗效果预测指标的效果的实证研究。
Stat Med. 1998 Sep 15;17(17):1923-42. doi: 10.1002/(sici)1097-0258(19980915)17:17<1923::aid-sim874>3.0.co;2-6.
5
Health outcomes associated with antihypertensive therapies used as first-line agents. A systematic review and meta-analysis.与用作一线药物的抗高血压疗法相关的健康结局。一项系统评价和荟萃分析。
JAMA. 1997 Mar 5;277(9):739-45.
6
The number needed to treat: a clinically useful nomogram in its proper context.需治疗人数：在恰当背景下的一种临床实用列线图。
BMJ. 1996 Feb 17;312(7028):426-9. doi: 10.1136/bmj.312.7028.426.
7
The framing effect of relative and absolute risk.相对风险和绝对风险的框架效应。
J Gen Intern Med. 1993 Oct;8(10):543-8. doi: 10.1007/BF02599636.
8
Evidence based purchasing: understanding results of clinical trials and systematic reviews.循证采购：理解临床试验和系统评价的结果
BMJ. 1995 Oct 21;311(7012):1056-9; discussion 1059-60. doi: 10.1136/bmj.311.7012.1056.
9
A randomized trial of propranolol in patients with acute myocardial infarction. I. Mortality results.一项关于普萘洛尔治疗急性心肌梗死患者的随机试验。I. 死亡率结果。
JAMA. 1982 Mar 26;247(12):1707-14. doi: 10.1001/jama.1982.03320370021023.
10
Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group.17187例疑似急性心肌梗死患者静脉注射链激酶、口服阿司匹林、两者并用或两者均不用的随机试验：ISIS-2。ISIS-2（第二次心肌梗死存活国际研究）协作组
Lancet. 1988 Aug 13;2(8607):349-60.