Koes B W, Bouter L M, van Mameren H, Essers A H, Verstegen G M, Hofhuizen D M, Houben J P, Knipschild P G
Department of Epidemiology and Biostatistics, University of Limburg, Maastricht, The Netherlands.
Spine (Phila Pa 1976). 1992 Jan;17(1):28-35. doi: 10.1097/00007632-199201000-00005.
In a randomized trial, the effectiveness of manual therapy, physiotherapy, continued treatment by the general practitioner, and placebo therapy (detuned ultrasound and detuned short-wave diathermy) were compared for patients (n = 256) with nonspecific back and neck complaints lasting for at least 6 weeks. The principle outcome measures were severity of the main complaint, global perceived effect, pain, and functional status. These are presented for 3, 6, and 12 weeks follow-up. Both physiotherapy and manual therapy decreased the severity of complaints more and had a higher global perceived effect compared to continued treatment by the general practitioner. Differences in effectiveness between physiotherapy and manual therapy could not be shown. A substantial part of the effect of manual therapy and physiotherapy appeared to be due to nonspecific (placebo) effects.
在一项随机试验中，对256名患有持续至少6周的非特异性背部和颈部疼痛的患者，比较了手法治疗、物理治疗、全科医生持续治疗以及安慰剂治疗（失谐超声和失谐短波透热疗法）的效果。主要结局指标为主诉严重程度、整体感知效果、疼痛和功能状态。这些指标在随访3周、6周和12周时呈现。与全科医生的持续治疗相比，物理治疗和手法治疗均更能减轻主诉严重程度，且整体感知效果更好。物理治疗和手法治疗之间的效果差异未显示出来。手法治疗和物理治疗的大部分效果似乎归因于非特异性（安慰剂）效应。
