血液的氧饱和度依赖性吸收与散射。

Oxygen saturation-dependent absorption and scattering of blood.

作者信息

Faber Dirk J, Aalders Maurice C G, Mik Egbert G, Hooper Brett A, van Gemert Martin J C, van Leeuwen Ton G

机构信息

Laser Center, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

出版信息

Phys Rev Lett. 2004 Jul 9;93(2):028102. doi: 10.1103/PhysRevLett.93.028102. Epub 2004 Jul 8.

DOI:10.1103/PhysRevLett.93.028102

PMID:15323954

Abstract

We report on the scattering properties of oxygenated and deoxygenated whole blood from 250 to 1000 nm. We determine the complex refractive index of oxygenated and deoxygenated hemoglobin using a Kramers-Kronig analysis and optical coherence tomography measurements. Combining these data with Mie theory, the scattering properties are calculated. The strong oxygen saturation dependent scattering effects should be taken into account in the data analysis of optical oxymetry.

摘要

我们报告了250至1000纳米范围内氧合和脱氧全血的散射特性。我们使用克拉默斯-克勒尼希分析和光学相干断层扫描测量来确定氧合和脱氧血红蛋白的复折射率。将这些数据与米氏理论相结合，计算出散射特性。在光学血氧测定的数据分析中应考虑到强烈的氧饱和度依赖性散射效应。