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Phylogenetic origin and virulence genotype in relation to resistance to fluoroquinolones and/or extended-spectrum cephalosporins and cephamycins among Escherichia coli isolates from animals and humans.来自动物和人类的大肠杆菌分离株中与对氟喹诺酮类和/或广谱头孢菌素及头霉素耐药性相关的系统发育起源和毒力基因型
J Infect Dis. 2003 Sep 1;188(5):759-68. doi: 10.1086/377455. Epub 2003 Aug 15.
2
Risk factors for fluoroquinolone resistance in nosocomial Escherichia coli and Klebsiella pneumoniae infections.医院内大肠杆菌和肺炎克雷伯菌感染中氟喹诺酮耐药的危险因素。
Arch Intern Med. 2002 Nov 25;162(21):2469-77. doi: 10.1001/archinte.162.21.2469.
3
Are quinolone-resistant uropathogenic Escherichia coli less virulent?耐喹诺酮的尿路致病性大肠杆菌毒力更低吗？
J Infect Dis. 2002 Oct 1;186(7):1039-42. doi: 10.1086/342955. Epub 2002 Sep 13.
4
Epidemiological investigation of fluoroquinolone resistance in infections due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae.产超广谱β-内酰胺酶大肠埃希菌和肺炎克雷伯菌所致感染中氟喹诺酮耐药性的流行病学调查
Clin Infect Dis. 2001 Oct 15;33(8):1288-94. doi: 10.1086/322667. Epub 2001 Sep 14.
5
Rapid and simple determination of the Escherichia coli phylogenetic group.快速简便地测定大肠杆菌的系统发育群。
Appl Environ Microbiol. 2000 Oct;66(10):4555-8. doi: 10.1128/AEM.66.10.4555-4558.2000.
6
Extended virulence genotypes of Escherichia coli strains from patients with urosepsis in relation to phylogeny and host compromise.与系统发育和宿主损害相关的尿路感染败血症患者大肠杆菌菌株的扩展毒力基因型
J Infect Dis. 2000 Jan;181(1):261-72. doi: 10.1086/315217.
7
Multiple antibiotic-resistant Klebsiella and Escherichia coli in nursing homes.养老院中多重耐药的克雷伯菌和大肠杆菌
JAMA. 1999 Feb 10;281(6):517-23. doi: 10.1001/jama.281.6.517.
8
Low-level colonization and infection with ciprofloxacin-resistant gram-negative bacilli in a skilled nursing facility.在一家专业护理机构中，耐环丙沙星革兰氏阴性杆菌的低水平定植与感染
Am J Infect Control. 1998 Dec;26(6):552-7. doi: 10.1053/ic.1998.v26.a88774.
9
Antimicrobial resistance in isolates from inpatients and outpatients in the United States: increasing importance of the intensive care unit.美国住院患者和门诊患者分离株中的抗菌药物耐药性：重症监护病房的重要性日益增加。
Clin Infect Dis. 1997 Feb;24(2):211-5. doi: 10.1093/clinids/24.2.211.
10
Infections and antibiotic resistance in nursing homes.养老院中的感染与抗生素耐药性。
Clin Microbiol Rev. 1996 Jan;9(1):1-17. doi: 10.1128/CMR.9.1.1.

疗养院居民中肠道外致病性大肠杆菌的定植及其与氟喹诺酮耐药性的关系。

Colonization with extraintestinal pathogenic Escherichia coli among nursing home residents and its relationship to fluoroquinolone resistance.

作者信息

Maslow Joel N, Lautenbach Ebbing, Glaze Thomas, Bilker Warren, Johnson James R

机构信息

Section of Infectious Diseases, Veterans Affairs Medical Center, University and Woodland Ave., Philadelphia, PA 19104, USA.

出版信息

Antimicrob Agents Chemother. 2004 Sep;48(9):3618-20. doi: 10.1128/AAC.48.9.3618-3620.2004.

DOI:10.1128/AAC.48.9.3618-3620.2004
PMID:15328142
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC514789/
Abstract

In a cross-sectional fecal prevalence survey involving 49 residents of a Veterans Affairs nursing home, 59% of subjects were colonized with extraintestinal pathogenic Escherichia coli (ExPEC), 22% were colonized with adhesin-positive E. coli, and 51% were colonized with fluoroquinolone-resistant E. coli. Among 80 unique isolates, adhesins correlated negatively and aerobactin correlated positively with fluoroquinolone resistance.

摘要

在一项涉及一家退伍军人事务疗养院49名居民的横断面粪便患病率调查中，59%的受试者被肠道外致病性大肠杆菌（ExPEC）定植，22%被黏附素阳性大肠杆菌定植，51%被氟喹诺酮耐药大肠杆菌定植。在80株独特的分离株中，黏附素与氟喹诺酮耐药呈负相关，气杆菌素与氟喹诺酮耐药呈正相关。