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动态轮廓眼压测量法:对人类尸体眼睛的比较研究

Dynamic contour tonometry: a comparative study on human cadaver eyes.

作者信息

Kniestedt Christoph, Nee Michelle, Stamper Robert L

机构信息

Department of Ophthalmology, University of California-San Francisco, 10 Kirkham Street, San Francisco, CA 94143, USA.

出版信息

Arch Ophthalmol. 2004 Sep;122(9):1287-93. doi: 10.1001/archopht.122.9.1287.

DOI:10.1001/archopht.122.9.1287
PMID:15364707
Abstract

OBJECTIVE

To compare intraocular pressure measurements obtained by recently introduced dynamic contour tonometry (DCT), Goldmann applanation tonometry (GAT), pneumatonometry (PTG), and intracameral manometry in human cadaver eyes.

METHODS

Sixteen freshly enucleated human cadaver eyes were deepithelialized and dehydrated with dextran. A tube was placed in the anterior chamber and connected to a transducer and to a bottle system filled with balanced salt solution. The pressure in the eye was then altered between 5 mm Hg and 58 mm Hg. Intraocular pressure measurements were obtained with DCT, GAT, and PTG at each manometric pressure reading.

RESULTS

On average, DCT values measured 0.58 +/- 0.70 mm Hg higher than real intracameral pressure. The GAT and PGT showed consistently lower values, -4.01 +/- 1.76 mm Hg and -5.09 +/- 2.61 mm Hg, respectively. At all bottle heights, DCT values were significantly closer to the reference pressure than GAT and PTG (P<.001).

CONCLUSIONS

Measurement with DCT provides IOP values significantly closer to true manometric levels than either GAT or PTG. Further studies are warranted to determine its reliability in patients and the effect of corneal thickness.

摘要

目的

比较最近推出的动态轮廓眼压计(DCT)、Goldmann压平眼压计(GAT)、气动眼压计(PTG)和前房测压法在人尸体眼中所测得的眼压值。

方法

16只新鲜摘除的人尸体眼经去上皮处理并用右旋糖酐脱水。在前房放置一根导管,将其连接到一个传感器以及一个装有平衡盐溶液的瓶系统。然后将眼内压力在5毫米汞柱至58毫米汞柱之间改变。在每个测压压力读数时,用DCT、GAT和PTG测量眼压。

结果

平均而言,DCT测得的值比实际前房压力高0.58±0.70毫米汞柱。GAT和PGT的值始终较低,分别为-4.01±1.76毫米汞柱和-5.09±2.61毫米汞柱。在所有瓶高情况下,DCT测得的值比GAT和PTG更接近参考压力(P<0.001)。

结论

与GAT或PTG相比,用DCT测量提供的眼压值更接近真实的测压水平。有必要进一步研究以确定其在患者中的可靠性以及角膜厚度的影响。

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