Clarity Eye Institute, Vaughan, Canada.
Glaucoma Unit, Sydney Eye Hospital, Sydney, Australia.
Eye (Lond). 2018 May;32(5):915-923. doi: 10.1038/s41433-018-0033-3. Epub 2018 Feb 15.
Central corneal thickness (CCT) is an important parameter in the assessment of any potential glaucoma patient. While it affects prognosis in ocular hypertension, its value in patients diagnosed with glaucoma is less certain. There are several biological factors and genetic components that may influence glaucoma progression, which have been associated with thinner CCT. The CCT itself can be affected by several factors including ethnicity, age, sex, glaucoma medications, genetics, and the subtype of glaucoma. Besides, there is variability in the measurement of CCT between difference types of devices. These factors need to be considered in the evaluation of glaucoma patients' CCT and its effect on interpretation of intraocular pressure levels and risk stratification.
中央角膜厚度(CCT)是评估任何潜在青光眼患者的重要参数。虽然它会影响高眼压症的预后,但在诊断为青光眼的患者中,其价值尚不确定。有几个生物学因素和遗传成分可能会影响青光眼的进展,这些因素与 CCT 变薄有关。CCT 本身会受到多种因素的影响,包括种族、年龄、性别、青光眼药物、遗传和青光眼亚型。此外,不同类型的设备对 CCT 的测量值也存在差异。在评估青光眼患者的 CCT 及其对眼压水平解读和风险分层的影响时,需要考虑这些因素。