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习惯性打鼾的危险因素及自然史。

Risk factors and natural history of habitual snoring.

作者信息

Urschitz Michael S, Guenther Anke, Eitner Steffen, Urschitz-Duprat Pilar M, Schlaud Martin, Ipsiroglu Osman S, Poets Christian F

机构信息

Department of Neonatology, University Hospital of Tuebingen, Calwerstr. 7, 72076 Tuebingen, Germany.

出版信息

Chest. 2004 Sep;126(3):790-800. doi: 10.1378/chest.126.3.790.

Abstract

STUDY OBJECTIVE

It has been suggested that habitual snoring (HS) has adverse health outcomes in children. We aimed to identify risk factors for HS and determine its natural history in primary school children.

DESIGN

Cross-sectional, population-based cohort study.

SETTING

Twenty-seven primary schools located within the city limits of Hannover, Germany.

PARTICIPANTS

Third-grade primary school children.

MEASUREMENTS AND RESULTS

Snoring frequency and potential risk factors were investigated using parental questionnaires. Unadjusted and adjusted odds ratios (ORs) for HS and their 95% confidence intervals (CIs) were calculated. One year after the initial contact, snoring status was re-evaluated in habitual snorers. In total, 1,760 children were contacted, and 1,144 parents and their children (49% were girls) agreed to participate and returned a completed questionnaire. A body mass index >/= 90th percentile (OR, 3.5; 95% CI, 1.8 to 7.1), low maternal education (OR, 2.3; 95% CI, 1.1 to 4.7), regular daytime mouth breathing (OR, 7.4; 95% CI, 3.5 to 15.6), and a higher frequency of sore throats (OR, 17.6; 95% CI, 6.4 to 48.8) were independent risk factors for HS. Parental smoking and frequent infections were significantly but not independently associated with HS. The association of low maternal education and HS was higher in boys (OR, 4.4; 95% CI, 1.5 to 13.6; vs OR, 1.2; 95% CI, 0.4 to 3.6), while that of sore throats and HS was higher in girls (OR, 52.7; 95% CI, 6.0 to 460.2; vs OR, 13.3; 95% CI, 3.0 to 58.5). At follow-up, 39 of 80 eligible habitual snorers (48.8%) still snored regularly. Children who continued to snore differed significantly in maternal education, household smoking, snoring loudness, and prior ear, nose, throat surgery from those who had ceased to snore habitually.

CONCLUSIONS

Socioeconomic status, obesity, signs of nasal obstruction, and pharyngeal problems were independent risk factors for HS in these primary school children. The expression of HS varied considerably over time.

摘要

研究目的

有人提出习惯性打鼾(HS)对儿童健康有不良影响。我们旨在确定小学生HS的危险因素并确定其自然病程。

设计

基于人群的横断面队列研究。

地点

德国汉诺威市范围内的27所小学。

参与者

三年级小学生。

测量与结果

使用家长问卷调查打鼾频率和潜在危险因素。计算HS的未调整和调整比值比(OR)及其95%置信区间(CI)。在初次接触一年后,对习惯性打鼾者的打鼾状况进行重新评估。总共联系了1760名儿童,1144名家长及其子女(49%为女孩)同意参与并返回了完整的问卷。体重指数>/=第90百分位数(OR,3.5;95%CI,1.8至7.1)、母亲教育程度低(OR,2.3;95%CI,1.1至4.7)、白天经常张口呼吸(OR,7.4;95%CI,3.5至15.6)以及喉咙痛频率较高(OR,17.6;95%CI,6.4至48.8)是HS的独立危险因素。父母吸烟和频繁感染与HS有显著关联,但并非独立关联。母亲教育程度低与HS的关联在男孩中更高(OR,4.4;95%CI,1.5至13.6;相比之下,OR,1.2;95%CI,0.4至3.6),而喉咙痛与HS的关联在女孩中更高(OR,52.7;95%CI,6.0至460.2;相比之下,OR,13.3;95%CI,3.0至58.5)。在随访中,80名符合条件的习惯性打鼾者中有39名(48.8%)仍经常打鼾。继续打鼾的儿童在母亲教育程度、家庭吸烟情况、打鼾响度以及既往耳鼻喉手术方面与已停止习惯性打鼾的儿童有显著差异。

结论

社会经济地位、肥胖、鼻塞迹象和咽部问题是这些小学生HS的独立危险因素。HS的表现随时间有很大差异。

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