Schmidt K R, Pfeifer K J, Welter H, Ingrisch H, Heyde G
Rofo. 1979 Feb;130(2):200-4. doi: 10.1055/s-0029-1231253.
An attempt was made to reduce pain during femoral angiography by adding 1 mg. of Lidocaine/ml. contrast medium in the course of 95 examinations. In a further 87 patients, Diazepam was injected intravenously before the injection of the contrast-Lidocaine mixture. Pain and the feeling of heat was compared with a control group who received contrast medium with 10% physiological saline. There was a highly significant reduction in pain sensation as a result of Lidocaine; pain was further reduced by additional Diazepam, which also reduced heat sensation, but resulted in a fall in blood pressure. High risk patients did not suffer any significant complications. Lidocaine is well suited for out patients, but Diazepam requires a longer period of observation. General anaesthesia has been used only if patients insisted on it or if there was known contrast reaction.
在95例股动脉造影检查过程中，尝试通过在造影剂中每毫升添加1毫克利多卡因来减轻疼痛。在另外87例患者中，在注射含利多卡因的造影剂混合物之前静脉注射地西泮。将疼痛和热感与接受含10%生理盐水造影剂的对照组进行比较。利多卡因使疼痛感显著降低；额外使用地西泮进一步减轻了疼痛，同时也减轻了热感，但导致血压下降。高危患者未出现任何严重并发症。利多卡因非常适合门诊患者，但地西泮需要更长的观察时间。仅在患者坚持或已知有造影剂反应时才使用全身麻醉。
