Kesner Raymond P, Rogers Jason
Department of Psychology, University of Utah, Salt Lake City, UT 84112, USA.
Neurobiol Learn Mem. 2004 Nov;82(3):199-215. doi: 10.1016/j.nlm.2004.05.007.
It is proposed that memory is organized into event-based, knowledge-based, and rule-based memory systems. Furthermore, each system is composed of the same set of multiple attributes and characterized by a set of process oriented operating characteristics that are mapped onto multiple neural regions and interconnected neural circuits. Based on this theoretical model of memory, it is possible to investigate the independence and interaction among brain regions between any two systems for any of the proposed attributes or processes. This applies also to the investigation of independence and interactions between any two attributes within a system and between processes associated with a system for any of the proposed attributes. In this article, research evidence is presented to suggest that there are both dissociations and interactions between the hippocampus and caudate nucleus in mediating spatial and response attributes within the event-based memory system, between the hippocampus and the parietal cortex in subserving the spatial attribute within the event-based and knowledge-based memory systems, and between the hippocampus and the prefrontal cortex in subserving the spatial attribute within the event-based and rule-based memory systems.
有人提出，记忆被组织成基于事件、基于知识和基于规则的记忆系统。此外，每个系统都由同一组多个属性组成，并具有一组面向过程的操作特征，这些特征映射到多个神经区域和相互连接的神经回路。基于这种记忆理论模型，有可能针对任何所提出的属性或过程，研究任意两个系统之间脑区的独立性和相互作用。这也适用于研究一个系统内任意两个属性之间以及与一个系统相关的过程之间对于任何所提出的属性的独立性和相互作用。在本文中，研究证据表明，在基于事件的记忆系统中，海马体和尾状核在介导空间和反应属性方面存在分离和相互作用；在基于事件和基于知识的记忆系统中，海马体和顶叶皮层在支持空间属性方面存在分离和相互作用；在基于事件和基于规则的记忆系统中，海马体和前额叶皮层在支持空间属性方面存在分离和相互作用。
